The purpose of the Telemetry Core Laboratory will be to provide facilities, resources, training and support to participants of the PPG for performing longitudinal in vivo physiologic analyses of cardiovascular function in conscious mice. Equipment available and protocols developed within the Core will allow investigators to not only measure real-time blood pressure, heart rate, autonomic activity and baroreflex function but also assess locomotor activity using implantable telemetry devices. This will be achieved by providing access to state-ofthe- art telemetric equipment and expertise. The Telemetry Core staff will offer supervision, maintenance, training and support regarding all aspects of telemetry (surgical implantation of telemeters and other related surgical methods, data acquisition and analysis, software support, quality control, etc.). Furthermore, the Core Director and Co-Director, along with experienced and skilled experts on the staff, will provide consultative services for planning, implementing and evaluating experiments. The Davisson laboratory, in collaboration with Data Sciences International (Arden Hills, MN) pioneered the use of telemetry for long-term, non-invasive monitoring of real-time blood pressure in conscious mice almost a decade ago, and a telemetry facility to record 16 mice continuously (32 on scheduled recording) has recently been established at her Weill laboratory. The establishment of the Telemetry Core facility will allow PPG investigators to assess cardiovascular function longitudinally in conscious mice in a variety of experimental paradigms.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL096571-05
Application #
8502539
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
5
Fiscal Year
2013
Total Cost
$215,442
Indirect Cost
$87,961
Name
Weill Medical College of Cornell University
Department
Type
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065
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