The Administrative Core will perform services that will encourage and facilitate interactions among Program participants and optimize the value and utilization ofthe scientific Cores. The Administrative Core will oversee the management and administration of this Program. These duties include review of Program projects, management of Program accounts, coordination of Program-related research meetings, and assistance to Program investigators in the preparation of progress reports. In addition, the Administrative Core will arrange weekly meetings of Program investigators and coworkers, visits by members ofthe External Advisory Committee, and the meetings of Internal Advisory Committee.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
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Heart, Lung, and Blood Initial Review Group (HLBP)
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Benaroya Research Institute at Virginia Mason
United States
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Wilson, S S; Tocchi, A; Holly, M K et al. (2015) A small intestinal organoid model of non-invasive enteric pathogen-epithelial cell interactions. Mucosal Immunol 8:352-61
Giannandrea, Matthew; Parks, William C (2014) Diverse functions of matrix metalloproteinases during fibrosis. Dis Model Mech 7:193-203
Chang, Mary Y; Tanino, Yoshinori; Vidova, Veronika et al. (2014) A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease. Matrix Biol 34:1-12
Smigiel, Kate S; Richards, Elizabeth; Srivastava, Shivani et al. (2014) CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets. J Exp Med 211:121-36
Srivastava, Shivani; Koch, Meghan A; Pepper, Marion et al. (2014) Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection. J Exp Med 211:961-74
Srivastava, Shivani; Koch, Lisa K; Campbell, Daniel J (2014) IFN?R signaling in effector but not regulatory T cells is required for immune dysregulation during type I IFN-dependent inflammatory disease. J Immunol 193:2733-42
Gharib, Sina A; Johnston, Laura K; Huizar, Isham et al. (2014) MMP28 promotes macrophage polarization toward M2 cells and augments pulmonary fibrosis. J Leukoc Biol 95:9-18
Smigiel, Kate S; Srivastava, Shivani; Stolley, J Michael et al. (2014) Regulatory T-cell homeostasis: steady-state maintenance and modulation during inflammation. Immunol Rev 259:40-59
Chang, Mary Y; Tanino, Yoshinori; Vidova, Veronika et al. (2014) Reprint of: A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease. Matrix Biol 35:162-73
Kang, Inkyung; Yoon, Dong Won; Braun, Kathleen R et al. (2014) Expression of versican V3 by arterial smooth muscle cells alters tumor growth factor ? (TGF?)-, epidermal growth factor (EGF)-, and nuclear factor ?B (NF?B)-dependent signaling pathways, creating a microenvironment that resists monocyte adhesion. J Biol Chem 289:15393-404

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