S-nitrosylation study will lead to a potential clinical importance in the area of asthma, cystic fibrosis, and pulmonary arterial hypertension. The participating investigators require state-of-the-art imaging methodologies to demonstrate in 3- or 4-dimension of S-nitrosothiol localization and trafficking in neuronal, endothelial and epithelial cells. As outlined below the W.M. Keck Center for Cellular Imaging (KCCI) is one of the leading centers internationally in the area of advanced molecular imaging. We have the necessary space and imaging systems to implement successfully the participating investigator projects.

Agency
National Institute of Health (NIH)
Type
Research Program Projects (P01)
Project #
5P01HL101871-05
Application #
8646971
Study Section
Heart, Lung, and Blood Program Project Review Committee (HLBP)
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
City
Cleveland
State
OH
Country
United States
Zip Code
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