Core B is designed to specifically support the development of """"""""translational glycobiologists"""""""", possessing a firm glycoscience-based mechanistic orientation to medically-oriented issues. By intent, we seek to train individuals that, by virtue of this PEG, will possess broad-based knowledge of glycan chemistry and biochemistry coupled with the motivation and preparation to apply this considerable glycoscience knowledge to drive forward the development of transformative therapeutics for heart, lung and blood diseases. To achieve this goal, the Core will provide training that seamlessly incorporates practical skills experience with glycoscience education altogether with bioscience education and the greater appreciation of human physiology, human health and human welfare. By hosting relevant seminars, this Core will also serve to bridge the ever-widening gap between the glycoscience community and practicing clinicians.
Core B will provide training that seamlessly incorporates practical skills experience with glycoscience education altogether with bioscience education and the greater appreciation of human physiology, human health and human welfare.
|PachÃ³n-PeÃ±a, Gisela; Donnelly, Conor; Ruiz-CaÃ±ada, Catalina et al. (2016) A Glycovariant of Human CD44 is Characteristically Expressed on Human Mesenchymal Stem Cells. Stem Cells :|
|Dykstra, Brad; Lee, Jungmin; Mortensen, Luke J et al. (2016) Glycoengineering of E-Selectin Ligands by Intracellular versus Extracellular Fucosylation Differentially Affects Osteotropism of Human Mesenchymal Stem Cells. Stem Cells 34:2501-2511|
|Neelamegham, Sriram; Mahal, Lara K (2016) Multi-level regulation of cellular glycosylation: from genes to transcript to enzyme to structure. Curr Opin Struct Biol 40:145-152|
|Li, Renhao; Hoffmeister, Karin M; Falet, HervÃ© (2016) Glycans and the platelet life cycle. Platelets 27:505-11|
|Sackstein, Robert (2016) Fulfilling Koch's postulates in glycoscience: HCELL, GPS and translational glycobiology. Glycobiology 26:560-70|
|Yao, J; Zhang, L; Hu, L et al. (2016) Tumorigenic potential is restored during differentiation in fusion-reprogrammed cancer cells. Cell Death Dis 7:e2314|
|Hoffmeister, Karin M; Falet, HervÃ© (2016) Platelet clearance by the hepatic Ashwell-Morrell receptor: mechanisms and biological significance. Thromb Res 141 Suppl 2:S68-72|
|Xu, Yu-Xin; Ashline, David; Liu, Li et al. (2015) The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis. J Lipid Res 56:266-76|
|Mondal, Nandini; Buffone Jr, Alexander; Stolfa, Gino et al. (2015) ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes. Blood 125:687-96|
|Grozovsky, Renata; Giannini, Silvia; Falet, HervÃ© et al. (2015) Regulating billions of blood platelets: glycans and beyond. Blood 126:1877-84|
Showing the most recent 10 out of 48 publications