Core B is designed to specifically support the development of "translational glycobiologists", possessing a firm glycoscience-based mechanistic orientation to medically-oriented issues. By intent, we seek to train individuals that, by virtue of this PEG, will possess broad-based knowledge of glycan chemistry and biochemistry coupled with the motivation and preparafion to apply this considerable glycoscience knowledge to drive fonward the development of transformative therapeutics for heart, lung and blood diseases. To achieve this goal, the Core will provide training that seamlessly incorporates practical skills experience with glycoscience education altogether with bioscience education and the greater appreciation of human physiology, human health and human welfare. By hosfing relevant seminars, this Core will also serve to bridge the ever-widening gap between the glycoscience community and practicing clinicians.
Core B will provide training that seamlessly incorporates practical skills experience with glycoscience education altogether with bioscience education and the greater appreciation of human physiology, human health and human welfare.
|Liu, Zhi-Jian; Hoffmeister, Karin M; Hu, Zhongbo et al. (2014) Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan. Blood 123:3381-9|
|Liu, Gang; Neelamegham, Sriram (2014) A computational framework for the automated construction of glycosylation reaction networks. PLoS One 9:e100939|
|Nasirikenari, Mehrab; Veillon, Lucas; Collins, Christine C et al. (2014) Remodeling of marrow hematopoietic stem and progenitor cells by non-self ST6Gal-1 sialyltransferase. J Biol Chem 289:7178-89|
|Dauber, Andrew; Ercan, Altan; Lee, Jack et al. (2014) Congenital disorder of fucosylation type 2c (LADII) presenting with short stature and developmental delay with minimal adhesion defect. Hum Mol Genet 23:2880-7|
|Lee, Melissa M; Nasirikenari, Mehrab; Manhardt, Charles T et al. (2014) Platelets support extracellular sialylation by supplying the sugar donor substrate. J Biol Chem 289:8742-8|
|Ashline, David J; Hanneman, Andrew J S; Zhang, Hailong et al. (2014) Structural documentation of glycan epitopes: sequential mass spectrometry and spectral matching. J Am Soc Mass Spectrom 25:444-53|
|Batal, Ibrahim; Azzi, Jamil; Mounayar, Marwan et al. (2014) The mechanisms of up-regulation of dendritic cell activity by oxidative stress. J Leukoc Biol 96:283-93|
|Silvescu, Cristina I; Sackstein, Robert (2014) G-CSF induces membrane expression of a myeloperoxidase glycovariant that operates as an E-selectin ligand on human myeloid cells. Proc Natl Acad Sci U S A 111:10696-701|
|Dykstra, Brad; Bystrykh, Leonid V (2014) No monkeying around: clonal tracking of stem cells and progenitors in the macaque. Cell Stem Cell 14:419-20|
|Cabral, M Guadalupe; Silva, Zelia; Ligeiro, Dario et al. (2013) The phagocytic capacity and immunological potency of human dendritic cells is improved by *2,6-sialic acid deficiency. Immunology 138:235-45|
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