Abstract

The principal objective of the Biostatistics and Data Management Core Facility is to provide a full collaborative scientific core for research design, conduct, data management and data analysis support for the program projects and cores. That includes preparation of code books, assignment of ID numbers, integration of data from different sources, responsibility for data quality assurance and the maintenance of clinical trial databases and preparing data quality control reports. Dr. Qaqish will be responsible for managing the day-today activities of the Core, and tracking the use of Core resources. He will be the lead statistician in the Core, with contributions from Dr. Kosorok in the area of personalized medicine treatment regimes. Dr. Qaqish and Dr. Kosorok will provide advice on statistical issues that arise in the design and analysis of studies and experiments in the program projects as well as in the other supporting cores. They will also participate in preparing manuscripts, reports and presentations.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
1P01HL108808-01A1
Application #
8292409
Study Section
Special Emphasis Panel (ZHL1-CSR-Q (F1))
Project Start
Project End
Budget Start
2012-06-15
Budget End
2013-05-31
Support Year
1
Fiscal Year
2012
Total Cost
$123,391
Indirect Cost
$40,019

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Abdullah, Lubna H; Coakley, Raymond; Webster, Megan J et al. (2018) Mucin Production and Hydration Responses to Mucopurulent Materials in Normal versus Cystic Fibrosis Airway Epithelia. Am J Respir Crit Care Med 197:481-491
Yu, Dongfang; Saini, Yogesh; Chen, Gang et al. (2018) Loss of ? Epithelial Sodium Channel Function in Meibomian Glands Produces Pseudohypoaldosteronism 1-Like Ocular Disease in Mice. Am J Pathol 188:95-110
Muhlebach, Marianne S; Hatch, Joseph E; Einarsson, Gisli G et al. (2018) Anaerobic bacteria cultured from cystic fibrosis airways correlate to milder disease: a multisite study. Eur Respir J 52:
Livraghi-Butrico, Alessandra; Wilkinson, Kristen J; Volmer, Allison S et al. (2018) Lung disease phenotypes caused by overexpression of combinations of ?-, ?-, and ?-subunits of the epithelial sodium channel in mouse airways. Am J Physiol Lung Cell Mol Physiol 314:L318-L331
Chen, Gang; Volmer, Allison S; Wilkinson, Kristen J et al. (2018) Role of Spdef in the Regulation of Muc5b Expression in the Airways of Naive and Mucoobstructed Mice. Am J Respir Cell Mol Biol 59:383-396
Bennett, William D; Zeman, Kirby L; Laube, Beth L et al. (2018) Homogeneity of Aerosol Deposition and Mucociliary Clearance are Improved Following Ivacaftor Treatment in Cystic Fibrosis. J Aerosol Med Pulm Drug Deliv 31:204-211
Ge, Ting; Grest, Gary S; Rubinstein, Michael (2018) Nanorheology of Entangled Polymer Melts. Phys Rev Lett 120:057801
Reighard, Katelyn P; Ehre, Camille; Rushton, Zachary L et al. (2017) Role of Nitric Oxide-Releasing Chitosan Oligosaccharides on Mucus Viscoelasticity. ACS Biomater Sci Eng 3:1017-1026
Zhou, Jinsheng; Wang, Yanqian; Menard, Laurent D et al. (2017) Enhanced nanochannel translocation and localization of genomic DNA molecules using three-dimensional nanofunnels. Nat Commun 8:807
Livraghi-Butrico, A; Grubb, B R; Wilkinson, K J et al. (2017) Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease. Mucosal Immunol 10:829

Showing the most recent 10 out of 76 publications