Core A will provide administrative support for all investigators in the Program by providing essential administrative and scientific oversight, secretarial assistance, fiscal administration, and ensuring compliance with federal and institutional guidelines. The Core will be directed by Dr. Rama Mallampalli, who will have primary responsibility for executing these objectives. This Core will also coordinate all interdepartmental and inter-institutional arrangements to facilitate and optimize progress of scientific interactions. The specific objectives of the Core include: (i) to organize budgetary and personnel resources, (ii) to implement interaction between investigators by regular scientific meetings and seminars and data review meetings, and (iii) to coordinate regulatory and scientific research data results for reporting. The Core will also handle all regular meetings of both Internal and External advisory groups, arrange seminars, and optimize scientific synergy of participants.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
1P01HL114453-01A1
Application #
8643332
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
2014-01-03
Project End
2018-12-31
Budget Start
2014-01-03
Budget End
2014-12-31
Support Year
1
Fiscal Year
2014
Total Cost
$125,597
Indirect Cost
$43,641
Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
McKelvey, Alison C; Lear, Travis B; Dunn, Sarah R et al. (2016) RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity. Elife 5:
Nan, Ling; Jacko, Anastasia M; Tan, Jiangning et al. (2016) Ubiquitin carboxyl-terminal hydrolase-L5 promotes TGFβ-1 signaling by de-ubiquitinating and stabilizing Smad2/Smad3 in pulmonary fibrosis. Sci Rep 6:33116
Liu, Yuan; Mallampalli, Rama K (2016) Small molecule therapeutics targeting F-box proteins in cancer. Semin Cancer Biol 36:105-19
Lear, Travis; McKelvey, Alison C; Rajbhandari, Shristi et al. (2016) Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4. J Exp Med 213:1029-46
Harris, Leonard A; Hogg, Justin S; Tapia, José-Juan et al. (2016) BioNetGen 2.2: advances in rule-based modeling. Bioinformatics 32:3366-3368
Morel, Penelope A; Lee, Robin E C; Faeder, James R (2016) Demystifying the cytokine network: Mathematical models point the way. Cytokine :
Singamsetty, Srikanth; Shah, Faraaz Ali; Guo, Lanping et al. (2016) Early initiation of low-level parenteral dextrose induces an accelerated diabetic phenotype in septic C57BL/6J mice. Appl Physiol Nutr Metab 41:12-9
Mao, Gaowei; Qu, Feng; St Croix, Claudette M et al. (2016) Mitochondrial Redox Opto-Lipidomics Reveals Mono-Oxygenated Cardiolipins as Pro-Apoptotic Death Signals. ACS Chem Biol 11:530-40
Tejero, Jesús; Kapralov, Alexandr A; Baumgartner, Matthew P et al. (2016) Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences. Biochim Biophys Acta 1861:391-401
Buland, Justin R; Wasserloos, Karla J; Tyurin, Vladimir A et al. (2016) Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity. Am J Physiol Lung Cell Mol Physiol 311:L303-16

Showing the most recent 10 out of 60 publications