Core C is the Imaging Core. The purpose of this core is to provide access and training for the two Image Analysis Systems (Nikon E800 and E1000 fluorescent scopes with DIG optics and imaging software) and the three Confocal Laser Scanning Microscopes (FluoView, BioRad and Zeiss LSM510META Confocal Scanning Systems). The equipment will be used for density measures, cell counting, photodocumentation, production of digitized images and other needs as the projects require. There are three core locations: one on the second floor, one on the tenth floor of the Medical Research Building and the Zeiss LSM510META is located on the fourth floor of the contiguous Basic Science Building. For this program, all three are managed by a committee that consists of the Core Directors and Pi's on the program project and allows access to equipment that would otherwise be too expensive for each laboratory to own and maintain. Evidence of use by each project is described and it is clearly important for the production of data in all three projects. Personnel include a Core Director (0.60 cal. hrs.), a Core Co-Director (salary on ROS Analytical Core) and a research scientist (6.0 cal. hrs.). Note that the function of this Core compliments the Histopathology section of the ROS Analytical Core (Core B).

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
5P01NS011255-36
Application #
8375576
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
2014-03-31
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
36
Fiscal Year
2012
Total Cost
$49,323
Indirect Cost
$10,204
Name
University of Texas Medical Br Galveston
Department
Type
DUNS #
800771149
City
Galveston
State
TX
Country
United States
Zip Code
77555
Young, E E; Bryant, C D; Lee, S E et al. (2016) Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test. Genes Brain Behav 15:604-15
Carter, Michael W; Johnson, Kathia M; Lee, Jun Yeon et al. (2016) Comparison of Mechanical Allodynia and Recovery of Locomotion and Bladder Function by Different Parameters of Low Thoracic Spinal Contusion Injury in Rats. Korean J Pain 29:86-95
Hammell, D C; Zhang, L P; Ma, F et al. (2016) Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. Eur J Pain 20:936-48
Ji, Guangchen; Li, Zhen; Neugebauer, Volker (2015) Reactive oxygen species mediate visceral pain-related amygdala plasticity and behaviors. Pain 156:825-36
Neugebauer, Volker (2015) Amygdala pain mechanisms. Handb Exp Pharmacol 227:261-84
Yuan, Su-Bo; Ji, Guangchen; Li, Bei et al. (2015) A Wnt5a signaling pathway in the pathogenesis of HIV-1 gp120-induced pain. Pain 156:1311-9
Ji, Guangchen; Neugebauer, Volker (2014) CB1 augments mGluR5 function in medial prefrontal cortical neurons to inhibit amygdala hyperactivity in an arthritis pain model. Eur J Neurosci 39:455-66
Medina, Georgina; Ji, Guangchen; Grégoire, Stéphanie et al. (2014) Nasal application of neuropeptide S inhibits arthritis pain-related behaviors through an action in the amygdala. Mol Pain 10:32
Hassler, Shayne N; Johnson, Kathia M; Hulsebosch, Claire E (2014) Reactive oxygen species and lipid peroxidation inhibitors reduce mechanical sensitivity in a chronic neuropathic pain model of spinal cord injury in rats. J Neurochem 131:413-7
Gwak, Young S; Hassler, Shayne E; Hulsebosch, Claire E (2013) Reactive oxygen species contribute to neuropathic pain and locomotor dysfunction via activation of CamKII in remote segments following spinal cord contusion injury in rats. Pain 154:1699-708

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