Overall Objective: The purpose of this core is to provide centralized care, breeding, genotyping and quality control of transgenic and knockout animals for use by investigators in the program project. The core will maintain and distribute novel models for interrogating the importance of PPARy in the cerebral vasculature. The core will also provide a mechanism for the distribution of new experimental transgenic and knockout models to the Jackson Laboratory Induced Mutant Resource, and to program and non-program project investigators both at the University of Iowa and outside the institution. The core will implement the required "NIH Sharing Plan" for novel animal models. The main responsibilities of the Core will be: Provision of novel PPAR knockin and transgenic mice Maintenance of genetic stocks of other gene targeted and transgenic mice Genotyping transgenic and knockout animals Provision of experimental and control mice to investigators Quality Control

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
5P01NS024621-25
Application #
8375555
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
2012-04-01
Project End
2013-03-31
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
25
Fiscal Year
2012
Total Cost
$120,367
Indirect Cost
$40,121
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
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