Principal Investigator/Program Director (Last, first, middle) YOUNG. William L, M.D. ABSTRACT Under the direction of the Program Director, the Core provides centralized administrative coordination for all Projects and Cores. The Core is available to the Principal Investigators of the other Cores and Projects for administrative support and will provide assistance in progress report generation, manuscript preparation, and central scheduling of research meetings. The Core will orchestrate annual meetings of the Internal and External Advisory Committees to review scientific progress and chart the coming year's course. The Core will also organize meetings for oversight of the PPG and to facilitate exchange of data and scientific ideas between investigators.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
5P01NS044155-10
Application #
8451441
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
10
Fiscal Year
2013
Total Cost
$97,851
Indirect Cost
$34,588
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Kremer, P H C; Koeleman, B P C; Pawlikowska, L et al. (2015) Evaluation of genetic risk loci for intracranial aneurysms in sporadic arteriovenous malformations of the brain. J Neurol Neurosurg Psychiatry 86:524-9
Choi, Eun-Jung; Chen, Wanqiu; Jun, Kristine et al. (2014) Novel brain arteriovenous malformation mouse models for type 1 hereditary hemorrhagic telangiectasia. PLoS One 9:e88511
Han, Zhenying; Shen, Fanxia; He, Yue et al. (2014) Activation of ?-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress. PLoS One 9:e105711
Wada, Kosuke; Makino, Hiroshi; Shimada, Kenji et al. (2014) Translational research using a mouse model of intracranial aneurysm. Transl Stroke Res 5:248-51
Bendjilali, Nasrine; Nelson, Jeffrey; Weinsheimer, Shantel et al. (2014) Common variants on 9p21.3 are associated with brain arteriovenous malformations with accompanying arterial aneurysms. J Neurol Neurosurg Psychiatry 85:1280-3
Chen, Wanqiu; Young, William L; Su, Hua (2014) Induction of brain arteriovenous malformation in the adult mouse. Methods Mol Biol 1135:309-16
Rutledge, W Caleb; Ko, Nerissa U; Lawton, Michael T et al. (2014) Hemorrhage rates and risk factors in the natural history course of brain arteriovenous malformations. Transl Stroke Res 5:538-42
Takayanagi, Takehiko; Crawford, Kevin J; Kobayashi, Tomonori et al. (2014) Caveolin 1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase. Clin Sci (Lond) 126:785-94
Tada, Yoshiteru; Wada, Kosuke; Shimada, Kenji et al. (2014) Roles of hypertension in the rupture of intracranial aneurysms. Stroke 45:579-86
Sallach, Jessica; Di Pasquale, Giovanni; Larcher, Fernando et al. (2014) Tropism-modified AAV vectors overcome barriers to successful cutaneous therapy. Mol Ther 22:929-39

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