Administrative Core. The Administrative Core is composed of Dr, William Maixner (Program Director) and Dr. Richard Gracely (Associate Program Director). This Core will oversee the administrative activities of the Program and provide assistance to the individual subprojects in administrative matters. Most importantly, it will provide an infrastructure for the integration of findings from the individual subprojects for attainment of the Program's goals. Accordingly, the specific aims and funcfion of this core are to: 1. Coordinate the administrafive activifies of the Program and the individual subprojects (e.g., assist in the management of budgets and personnel). 2. Promote a scholariy environment by coordinafing the Program's seminar series and visits by external scientists. 3. Meet weekly and review administrative issues and concerns of the Program. 4. Meet monthly with the principal investigators and core directors to discuss progress and problems encountered by the individualsubprojects. 5. Assemble every six months Program investigators, postdoctoral fellows, graduate research assistants, consultants as available, and staff to (i) identify concordant and discordant research findings among subprojects, (ii) evaluate the Program's working hypotheses, (iii) determine if changes or refinements in protocols are needed, and (iv) promote creative thinking and reinforce interactions among the Program team members. 6. Coordinate annual meetings of the Program's External Scientific Advisory Committees with the entire invesfigative team.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
3P01NS045685-08S1
Application #
8457075
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
2015-03-31
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
8
Fiscal Year
2012
Total Cost
$1,022
Indirect Cost
$245
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Ciszek, Brittney P; O'Buckley, Sandra C; Nackley, Andrea G (2016) Persistent Catechol-O-methyltransferase-dependent Pain Is Initiated by Peripheral β-Adrenergic Receptors. Anesthesiology 124:1122-35
Moss, Chailee F; Damitz, Lynn A; Gracely, Richard H et al. (2016) Dorsal clitoral nerve injury following transobturator midurethral sling. J Pain Res 9:727-730
Oladosu, Folabomi A; Ciszek, Brittney P; O'Buckley, Sandra C et al. (2016) Novel intrathecal and subcutaneous catheter delivery systems in the mouse. J Neurosci Methods 264:119-28
Wu, Cindy; Damitz, Lynn; Karrat, Kimberly M et al. (2016) Clitoral Epidermal Inclusion Cyst Resection With Intraoperative Sensory Nerve Mapping Technique. Female Pelvic Med Reconstr Surg 22:e24-6
Ciszek, Brittney P; Khan, Asma A; Dang, Hong et al. (2015) MicroRNA expression profiles differentiate chronic pain condition subtypes. Transl Res 166:706-720.e11
Oladosu, Folabomi A; Conrad, Matthew S; O'Buckley, Sandra C et al. (2015) Mu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia. PLoS One 10:e0135711
Convertino, Marino; Samoshkin, Alexander; Gauthier, Josee et al. (2015) μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids. Prog Neuropsychopharmacol Biol Psychiatry 62:61-7
Applebaum, Elizabeth; Nackley, Andrea G; Bair, Eric et al. (2015) Genetic Variants in Cyclooxygenase-2 Contribute to Post-treatment Pain among Endodontic Patients. J Endod 41:1214-8
Oladosu, Folabomi A; Maixner, William; Nackley, Andrea G (2015) Alternative Splicing of G Protein-Coupled Receptors: Relevance to Pain Management. Mayo Clin Proc 90:1135-51
Meloto, Carolina B; Segall, Samantha K; Smith, Shad et al. (2015) COMT gene locus: new functional variants. Pain 156:2072-83

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