Our Project Coordination core has the following purposes: 1. Provide fiscal and administrative support for all projects. 2. Coordinate the interactions between our 3 projects with Core A and Core B. 3. Develop and maintain a networked database for cross-correlating findings from each project into a central depository that enables major progress milestones to be synthesized. 4. Organize the bimonthly meetings of Project Leaders and the yearly Neurovascular Program Retreat. 5. Organize the yearly joint retreat with the MGH Clinical Stroke Service. 6. Facilitate communications between Pis, Executive Committee and the Internal Advisory Committee. 7. Organize the Neurovascular Plasticity Seminar Series and link with ongoing seminars at MGH. 8. Connect, host and mentor new clinician-scientists within MGH (as needed, no cost).

National Institute of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Research Program Projects (P01)
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Application #
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
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Fiscal Year
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Massachusetts General Hospital
United States
Zip Code
Shindo, Akihiro; Maki, Takakuni; Mandeville, Emiri T et al. (2016) Astrocyte-Derived Pentraxin 3 Supports Blood-Brain Barrier Integrity Under Acute Phase of Stroke. Stroke 47:1094-100
Chung, David Y; Oka, Fumiaki; Ayata, Cenk (2016) Spreading Depolarizations: A Therapeutic Target Against Delayed Cerebral Ischemia After Subarachnoid Hemorrhage. J Clin Neurophysiol 33:196-202
Liang, Anna C; Mandeville, Emiri T; Maki, Takakuni et al. (2016) Effects of Aging on Neural Stem/Progenitor Cells and Oligodendrocyte Precursor Cells After Focal Cerebral Ischemia in Spontaneously Hypertensive Rats. Cell Transplant 25:705-14
Seidel, Jessica L; Escartin, Carole; Ayata, Cenk et al. (2016) Multifaceted roles for astrocytes in spreading depolarization: A target for limiting spreading depolarization in acute brain injury? Glia 64:5-20
Wu, Limin; Ramirez, Servio H; Andrews, Allison M et al. (2016) Neuregulin1-β decreases interleukin-1β-induced RhoA activation, myosin light chain phosphorylation, and endothelial hyperpermeability. J Neurochem 136:250-7
Xing, Changhong; Lo, Eng H (2016) Help-me signaling: Non-cell autonomous mechanisms of neuroprotection and neurorecovery. Prog Neurobiol :
Mandeville, Emiri T; Ayata, Cenk; Zheng, Yi et al. (2016) Translational MR Neuroimaging of Stroke and Recovery. Transl Stroke Res :
Egawa, Naohiro; Lok, Josephine; Washida, Kazuo et al. (2016) Mechanisms of Axonal Damage and Repair after Central Nervous System Injury. Transl Stroke Res :
Arai, Ken (2016) Stroke Literature Synopses: Basic Science. Stroke 47:e250-e251
Arai, Ken (2016) Stroke Literature Synopses: Basic Science. Stroke 47:e40-1

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