This core provides administrative support for the program project in the form of oversight of day to day interactions, data sharing, group meetings, and formulation of an external advisory board. The core PI is Gina Turrigiano, Professor of Biology, Brandeis University.
Failure of homeostasis is central to many disease states affecting the nervous system. By uncovering the fundamental components of firing rate sensors and their homeostatic regulators we will develop new insights into the pathophysiology and treatment of neurological and psychiatric disorders.
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|Gjorgjieva, Julijana; Drion, Guillaume; Marder, Eve (2016) Computational implications of biophysical diversity and multiple timescales in neurons and synapses for circuit performance. Curr Opin Neurobiol 37:44-52|
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|O'Leary, Timothy; Williams, Alex H; Franci, Alessio et al. (2014) Cell types, network homeostasis, and pathological compensation from a biologically plausible ion channel expression model. Neuron 82:809-21|