The Latino/Hispanic population is the largest minority in the US and the highest concentration of Latinos is along the US-Mexico Border. To address the specific needs of this population in cancer research and education, a partnership between The University of Texas-Pan American and the Cancer Center at The University of Texas Health Science Center at San Antonio is proposed. The goals of this application are to develop research and training partnerships to increase the cancer research base on the US-Mexico border. The projects proposed will not only develop translational research in basic science but also address cancer related health disparities in the Hispanic border population. The specific goals of the application are: 1. to develop and foster cancer research at UTPA;2. to foster research dedicated towards reducing the cancer burden of the Hispanic population with emphasis on the US-Mexico border, and 3. to increase the number of cancer researchers coming from South Texas. To accomplish these goals, two pilot projects and a training program are proposed. The first pilot project is a basic science project which will take advantage of the expertise at UTPA to synthesize polycyclic aromatic compounds and expertise at UTHSCSA to test these compounds as anticancer agents. The second pilot project is directed toward understanding the attitudes and decision making processes in genetic testing for increased breast cancer risk. The third project is a summer undergraduate program for UTPA students to work in laboratories and to learn about cancer biology with the goal of increasing the number of students from communities in South Texas interested in cancer research. This multidimensional approach will heighten cancer research and education in the Hispanic/Latino population along the Texas border.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Exploratory Grants (P20)
Project #
5P20CA138022-03
Application #
7928253
Study Section
Special Emphasis Panel (ZCA1-SRLB-H (O1))
Program Officer
Moten, Carmen P
Project Start
2008-09-26
Project End
2012-08-31
Budget Start
2010-09-01
Budget End
2011-08-31
Support Year
3
Fiscal Year
2010
Total Cost
$232,487
Indirect Cost
Name
University of Texas-Pan American
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
069444511
City
Edinburg
State
TX
Country
United States
Zip Code
78539
Bandyopadhyay, Debasish; Sanchez, Jorge L; Guerrero, Adrian M et al. (2015) Design, synthesis and biological evaluation of novel pyrenyl derivatives as anticancer agents. Eur J Med Chem 89:851-62
Su, Dejun; Pratt, William; Stimpson, Jim P et al. (2014) Uninsurance, underinsurance, and health care utilization in Mexico by US border residents. J Immigr Minor Health 16:607-12
Bandyopadhyay, Debasish; Cruz, Jessica; Morales, Liza D et al. (2013) A green approach toward quinoxalines and bis-quinoxalines and their biological evaluation against A431, human skin cancer cell lines. Future Med Chem 5:1377-90
Bandyopadhyay, Debasish; Mukherjee, Sanghamitra; Turrubiartes, Luis C et al. (2012) Ultrasound-assisted aza-Michael reaction in water: a green procedure. Ultrason Sonochem 19:969-73
Bandyopadhyay, Debasish; Mukherjee, Sanghamitra; Granados, Jose C et al. (2012) Ultrasound-assisted bismuth nitrate-induced green synthesis of novel pyrrole derivatives and their biological evaluation as anticancer agents. Eur J Med Chem 50:209-15
Bandyopadhyay, Debasish; Maldonado, Stephanie; Banik, Bimal K (2012) A microwave-assisted bismuth nitrate-catalyzed unique route toward 1,4-dihydropyridines. Molecules 17:2643-62
Banik, Bimal K; Becker, Frederick F (2010) Novel 6,12-disubstituted chrysene as potent anticancer agent: synthesis, in vitro and in vivo study. Eur J Med Chem 45:4687-91
Bandyopadhyay, Debasish; Mukherjee, Sanghamitra; Rodriguez, Robert R et al. (2010) An effective microwave-induced iodine-catalyzed method for the synthesis of quinoxalines via condensation of 1,2-diamines with 1,2-dicarbonyl compounds. Molecules 15:4207-12
Banik, Antara; Batta, Sahil; Bandyopadhyay, Debasish et al. (2010) A highly efficient bismuth salts-catalyzed route for the synthesis of ?-aminophosphonates. Molecules 15:8205-13
Bandyopadhyay, Debasish; Mukherjee, Sanghamitra; Banik, Bimal K (2010) An expeditious synthesis of N-substituted pyrroles via microwave-induced iodine-catalyzed reactions under solventless conditions. Molecules 15:2520-5