Drs. Kelvin O. Lim and Marilyn Carroll will serve as the Co-Directors of the CISA. Dr. Lim will be the Director of the Administrative Core. This Core will assure the smooth operation of the center. Dr. Lim is responsible for optimizing the translational approach to research and training, ensuring the ethical conduct of research and ensuring that all regulatory obligations are met, coordinating the various research projects and cores, assuming the fiscal responsibilities of the grant, and coordinating the resources and environment. The Administrative Core includes support for an Administrative Assistant who will assist Dr. Lim in the overall and day-to-day management issues of the IAC. To facilitate the generation of monthly progress reports and tracking the progress and activity across the clinical projects and cores, we will take advantage of a clinical research management software package (GRID) developed by Dr. Lim. A Steering Committee will be comprised of the Center Co-Directors and all Project and Core Directors. In order to optimize collaborations within the CISA and the University community, we will organize a bi-monthly collaborators meeting with all CISA investigators, students, and other interested parties. In addition to these meetings, an annual retreat will be arranged where the progress and direction of the CISA as a whole is reviewed and discussed. An Internal Advisory Board will be formed to provide ongoing, readily accessible review of the overall goals of the CISA, the scientific content of the individual studies, and our progress. This Board will meet formally twice a year. An External Advisory Board will be formed to provide advice to the CISA. Members of the External Advisory Board will be comprised of individuals with national and international repute with interest and expertise in different research aspects of preclinical and clinical neurobiological research into addiction. The External Advisory Board will officially meet once a year.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Exploratory Grants (P20)
Project #
5P20DA024196-04
Application #
8099039
Study Section
Special Emphasis Panel (ZDA1)
Project Start
Project End
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
4
Fiscal Year
2010
Total Cost
$70,046
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Chavarria-Siles, Ivan; White, Tonya; de Leeuw, Christiaan et al. (2016) Myelination-related genes are associated with decreased white matter integrity in schizophrenia. Eur J Hum Genet 24:381-6
Radke, Anna K; Zlebnik, Natalie E; Carroll, Marilyn E (2015) Cocaine withdrawal in rats selectively bred for low (LoS) versus high (HiS) saccharin intake. Pharmacol Biochem Behav 129:51-5
Holtz, Nathan A; Carroll, Marilyn E (2015) Cocaine self-administration punished by intravenous histamine in adolescent and adult rats. Behav Pharmacol 26:393-7
Camchong, Jazmin; Macdonald 3rd, Angus W; Mueller, Bryon A et al. (2014) Changes in resting functional connectivity during abstinence in stimulant use disorder: a preliminary comparison of relapsers and abstainers. Drug Alcohol Depend 139:145-51
Patzelt, Edward H; Kurth-Nelson, Zeb; Lim, Kelvin O et al. (2014) Excessive state switching underlies reversal learning deficits in cocaine users. Drug Alcohol Depend 134:211-217
Holtz, Nathan A; Anker, Justin J; Regier, Paul S et al. (2013) Cocaine self-administration punished by i.v. histamine in rat models of high and low drug abuse vulnerability: effects of saccharin preference, impulsivity, and sex. Physiol Behav 122:32-8
Radke, Anna K; Holtz, Nathan A; Gewirtz, Jonathan C et al. (2013) Reduced emotional signs of opiate withdrawal in rats selectively bred for low (LoS) versus high (HiS) saccharin intake. Psychopharmacology (Berl) 227:117-26
Jones, Jessica A H; Lim, Kelvin O; Wozniak, Jeffrey R et al. (2013) Context-processing abilities in chronic cocaine users. Psychol Addict Behav 27:687-95
Wisner, Krista M; Atluri, Gowtham; Lim, Kelvin O et al. (2013) Neurometrics of intrinsic connectivity networks at rest using fMRI: retest reliability and cross-validation using a meta-level method. Neuroimage 76:236-51
Holtz, Nathan A; Carroll, Marilyn E (2013) Escalation of i.v. cocaine intake in peri-adolescent vs. adult rats selectively bred for high (HiS) vs. low (LoS) saccharin intake. Psychopharmacology (Berl) 227:243-50

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