The Clinical and Educational Core (CEC;Core 2) will assume Center-wide responsibility for four major components of the ExCITRA (P20), including: 1) the recruitment, screening, diagnostic assessment, and clinical care of all human research participants;2) the comprehensive neurocognitive assessment of all subjects successfully meeting eligibility criteria;3) the concurrent psychopharmacologic characterization of individuals'subjective, behavioral, and neurocognitive responses to stimulant self-administration (cocaine in cocaine dependent subjects) and/or administration (methylphenidate in cocaine dependent and healthy control subjects);and, 4) the coordination of research career development of affiliated trainees in the interdisciplinary and translational neurobiology of drug addicfion.
The function of the Clinical and Education Core provides direct support to Projects 1 and 2 in the exploratory center and coordinates educational efforts across the enitre Center. Thus the function of the Core is essential to the translational research mission and goals of understanding the neurobiology of drug addiction.
|Worhunsky, Patrick D; Potenza, Marc N; Rogers, Robert D (2017) Alterations in functional brain networks associated with loss-chasing in gambling disorder and cocaine-use disorder. Drug Alcohol Depend 178:363-371|
|Yip, Sarah W; Morie, Kristen P; Xu, Jiansong et al. (2017) Shared microstructural features of behavioral and substance addictions revealed in areas of crossing fibers. Biol Psychiatry Cogn Neurosci Neuroimaging 2:188-195|
|Ren, Yudan; Fang, Jun; Lv, Jinglei et al. (2017) Assessing the effects of cocaine dependence and pathological gambling using group-wise sparse representation of natural stimulus FMRI data. Brain Imaging Behav 11:1179-1191|
|Worhunsky, Patrick D; Matuskey, David; Gallezot, Jean-Dominique et al. (2017) Regional and source-based patterns of [11C]-(+)-PHNO binding potential reveal concurrent alterations in dopamine D2 and D3 receptor availability in cocaine-use disorder. Neuroimage 148:343-351|
|Xu, Jiansong; Potenza, Marc N; Calhoun, Vince D et al. (2016) Large-scale functional network overlap is a general property of brain functional organization: Reconciling inconsistent fMRI findings from general-linear-model-based analyses. Neurosci Biobehav Rev 71:83-100|
|Schulte, Erica M; Yokum, Sonja; Potenza, Marc N et al. (2016) Neural systems implicated in obesity as an addictive disorder: from biological to behavioral mechanisms. Prog Brain Res 223:329-46|
|Pitts, Elizabeth G; Taylor, Jane R; Gourley, Shannon L (2016) Prefrontal cortical BDNF: A regulatory key in cocaine- and food-reinforced behaviors. Neurobiol Dis 91:326-35|
|Balodis, Iris M; Kober, Hedy; Worhunsky, Patrick D et al. (2016) Neurofunctional Reward Processing Changes in Cocaine Dependence During Recovery. Neuropsychopharmacology 41:2112-21|
|Gogliettino, Alex R; Potenza, Marc N; Yip, Sarah W (2016) White matter development and tobacco smoking in young adults: A systematic review with recommendations for future research. Drug Alcohol Depend 162:26-33|
|Gourley, Shannon L; Zimmermann, Kelsey S; Allen, Amanda G et al. (2016) The Medial Orbitofrontal Cortex Regulates Sensitivity to Outcome Value. J Neurosci 36:4600-13|
Showing the most recent 10 out of 114 publications