The Administrative core directed by Dr. Marshall Stoller and his associate directors Drs. Pankaj Kapahi and Thomas Chi will be responsible for creating an interdisciplinary center for prevention of recurrent nephrolithiasis. The Administrative core will coordinate between the members of the team to ensure smooth progress of the project. The Administrative core will create an interdisciplinary atmosphere so investigators from varied disciplines including, human clinicians, fly geneticists, physiologists, veterinarian and model developers can work seamlessly to achieve their aims. Consistent communication will occur via email and scheduled meetings. This Administrative core will ensure communication between all parties (of disparate disciplines and locations) in a collegial, collaborative and productive manner with an aim to create synergistic interactions. The critical purpose of the Administrative Core is to maintain an integrated team working in a cohesive, respectful, and honest fashion, and disperse its findings to the scientific community at large. The 3 major aims of the Administrative core will include: 1) establishing an interdisciplinary center; 2) ensuring efficient management of resources within the center; and 3) developing interactions with the wider research community. The Administrative Core will facilitate communication between other members of the George M. O?Brien Urology Centers through collaborations and various urology meetings. It will also bring divergent groups of high school, college, medical and Master?s students, urologic and non-urologic medical residents, post-doctoral fellows, coordinators, mathematical modelers, and various principal investigators together into a coherent working group to understand the multiple facets involved to better understand and to help prevent recurrent stone disease.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Exploratory Grants (P20)
Project #
5P20DK100863-04
Application #
9144790
Study Section
Special Emphasis Panel (ZDK1-GRB-S)
Project Start
Project End
Budget Start
2016-08-01
Budget End
2017-07-31
Support Year
4
Fiscal Year
2016
Total Cost
$67,047
Indirect Cost
$24,746
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94118
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Usawachintachit, Manint; Tzou, David T; Hu, Weiguo et al. (2017) X-ray-free Ultrasound-guided Percutaneous Nephrolithotomy: How to Select the Right Patient? Urology 100:38-44
Taguchi, Kazumi; Yasui, Takahiro; Milliner, Dawn Schmautz et al. (2017) Genetic Risk Factors for Idiopathic Urolithiasis: A Systematic Review of the Literature and Causal Network Analysis. Eur Urol Focus 3:72-81
Bose, Neelanjan; Zee, Tiffany; Kapahi, Pankaj et al. (2017) Mass Spectrometry-based in vitro Assay to Identify Drugs that Influence Cystine Solubility. Bio Protoc 7:
Zee, Tiffany; Bose, Neelanjan; Zee, Jarcy et al. (2017) ?-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria. Nat Med 23:288-290
Hsi, Ryan S; Ramaswamy, Krishna; Ho, Sunita P et al. (2017) The origins of urinary stone disease: upstream mineral formations initiate downstream Randall's plaque. BJU Int 119:177-184
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Hudnall, Matthew; Usawachintachit, Manint; Metzler, Ian et al. (2017) Ultrasound Guidance Reduces Percutaneous Nephrolithotomy Cost Compared to Fluoroscopy. Urology 103:52-58
Chang, Helena C; Tzou, David T; Usawachintachit, Manint et al. (2016) Rationale and Design of the Registry for Stones of the Kidney and Ureter (ReSKU): A Prospective Observational Registry to Study the Natural History of Urolithiasis Patients. J Endourol 30:1332-1338
Chi, Thomas; Usawachintachit, Manint; Filippou, Pauline et al. (2016) Significant differences in struvite and cystine stone frequency seen among Chinese nephrolithiasis patients living in North America compared to those living in China. Transl Androl Urol 5:375-80

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