This Alteration and Renovation request will provide University of Alaska Anchorage (UAA), a primarily undergraduate partner institution that is the designated health campus of UA, with improved physical space in the form of a Clinical-Translational Research Center (CTRC). Funds in this Alteration and Renovation Core will be utilized to provide three functional spaces dedicated to research activities in the translational and clinical domains: 1) Reception/desk area for research staff member and research participant, 2) Physical exam and sample collection area, 3) Biosafety Level 2 (BSL-2) lab for sample processing and data acquisition. Expanding and promoting collaborative, interdisciplinary research is a primary component of the vision for health sciences at UA. The CTRC will provide dedicated space to allow UAA faculty to participate in biomedical research as teams, spanning the lab-subject-community research domains within the Alaska IDeA Network of Biomedical Research Excellence (INBRE)3 themes. The CTRC will leverage our biomedical research focus on basic leading to translational research to improve overall health in the state. Research teams will include both current INBRE faculty, as well as faculty primarily from the School of Nursing, the WWAMI (Washington, Wyoming, Alaska, Montana, and Idaho) School of Medical Education, the Department of Health Sciences, and the School of Allied Health which have historically not been affiliated with Alaska INBRE. The CTRC will achieve the following four goals;1) Allow faculty with significant prior experience in translational health sciences, but who have not participated in previous Alaska INBRE cycles, to become active, engaged participants to further build biomedical research capacity in Alaska, 2) Provide infrastructure to facilitate the development of research experiences, theses and dissertations of a translational nature for health professional undergraduate and graduate students, 3) Disseminate knowledge by using translational research strategies to address significant health problems for Alaska, 4) Increase the number of biomedical faculty using translational research approaches to address the unique environment, people and exposure to environmental agents in Alaska. These four goals support the overall programmatic goals of Alaska INBRES.

Public Health Relevance

By supporting faculty through this research infrastructure, we will increase their ability to succesfully compete for ROI grants and other sources of support. We will broaden our range of expertise in biomedical research and available resources, facilitating new collaborations with clinical entities. Building translational research capacity at UA is essential to understand One Health (interaction of environment, animals, and people).

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
2P20GM103395-14
Application #
8715975
Study Section
Special Emphasis Panel (ZGM1-TWD-7 (IN))
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
14
Fiscal Year
2014
Total Cost
$138,000
Indirect Cost
Name
University of Alaska Fairbanks
Department
Type
DUNS #
615245164
City
Fairbanks
State
AK
Country
United States
Zip Code
99709
Maulik, Malabika; Mitra, Swarup; Hunter, Skyler et al. (2018) Sir-2.1 mediated attenuation of ?-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Sci Rep 8:10216
Bassham, Susan; Catchen, Julian; Lescak, Emily et al. (2018) Repeated Selection of Alternatively Adapted Haplotypes Creates Sweeping Genomic Remodeling in Stickleback. Genetics 209:921-939
McFarlin, Kelly M; Perkins, Matt J; Field, Jennifer A et al. (2018) Biodegradation of Crude Oil and Corexit 9500 in Arctic Seawater. Front Microbiol 9:1788
Francian, Alexandra; Namen, Shelby; Stanley, Madigan et al. (2018) Intratumoral delivery of antigen with complement C3-bound liposomes reduces tumor growth in mice. Nanomedicine :
McGill, Colin M; Brown, Timothy J; Cheng, Yuan-Yin et al. (2018) Therapeutic Effect of Blueberry Extracts for Acute Myeloid Leukemia. Int J Biopharm Sci 1:
Smith, Lisa K; Kuhn, Thomas B; Chen, Jack et al. (2018) HHIV Associated Neurodegenerative Disorders: A New Perspective on the Role of Lipid Rafts in Gp120-Mediated Neurotoxicity. Curr HIV Res :
O'Brien, Kristin M; Crockett, Elizabeth L; Philip, Jacques et al. (2018) The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes. J Exp Biol 221:
Mitra, Swarup; Bult-Ito, Abel (2018) Attenuation of compulsive-like behavior by fluvoxamine in a non-induced mouse model of obsessive-compulsive disorder. Behav Pharmacol 29:299-305
Smeele, Zoe E; Burns, Jennifer M; Van Doorsaler, Koenraad et al. (2018) Diverse papillomaviruses identified in Weddell seals. J Gen Virol 99:549-557
Sticka, Kendra D; Schnurr, Theresia M; Jerome, Scott P et al. (2018) Exercise Increases Glucose Transporter-4 Levels on Peripheral Blood Mononuclear Cells. Med Sci Sports Exerc 50:938-944

Showing the most recent 10 out of 114 publications