of the Bioinformatics Core Facility. The role of the Bioinformatics Core is to facilitate the understanding, analysis, and interpretation of various types of data for RI-INBRE supported investigators at the network institutions. These data types include nucleotide and amino acid sequences, protein and peptide sequences, genes expression arrays, protein domains, and protein structures. The responsibilities of the Core also include website management, storage of digitized data for the RI-INBRE program, management of bioinformatics tools and software, participation in the shared research activities of the NEBC, and coordination of the monthly RI-INBRE seminar series. The Core is led by Dr. Hany Alashwal who coordinates the overall core activities including seminars, workshops and software/hardware acquisition, data storage and processing. The Bioinformatics Core aims to provide expert consultation by developing informatics strategy for analysis of complex data sets for RI-INBRE-supported investigators, and educate the faculty and students regarding 1 bioinformatics approaches for their research in the RI-INBRE thematic areas. Bioinformatics Core activities can be divided into improving education by offering courses, workshops, and seminars, developing and strengthening collaboration between the RI-INBRE investigators, and providing information technology support to the network .

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
2P20GM103430-14
Application #
8716000
Study Section
Special Emphasis Panel (ZGM1-TWD-7 (IN))
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-04-30
Support Year
14
Fiscal Year
2014
Total Cost
$105,731
Indirect Cost
$36,851
Name
University of Rhode Island
Department
Type
DUNS #
144017188
City
Kingston
State
RI
Country
United States
Zip Code
02881
Xu, Jialin; Donepudi, Ajay C; More, Vijay R et al. (2015) Deficiency in Nrf2 transcription factor decreases adipose tissue mass and hepatic lipid accumulation in leptin-deficient mice. Obesity (Silver Spring) 23:335-44
Bellono, Nicholas W; Najera, Julia A; Oancea, Elena (2014) UV light activates a G?q/11-coupled phototransduction pathway in human melanocytes. J Gen Physiol 143:203-14
Brennan, Christopher M; Mazzucca, Nicholas Q; Mezoian, Taylor et al. (2014) Reduced heme levels underlie the exponential growth defect of the Shewanella oneidensis hfq mutant. PLoS One 9:e109879
Oh, Donghoon; Nasrolahi Shirazi, Amir; Northup, Kevin et al. (2014) Enhanced cellular uptake of short polyarginine peptides through fatty acylation and cyclization. Mol Pharm 11:2845-54
Nasrolahi Shirazi, Amir; Tiwari, Rakesh K; Oh, Donghoon et al. (2014) Cyclic peptide-selenium nanoparticles as drug transporters. Mol Pharm 11:3631-41
Lin, Qiushi; Aihara, Arihiro; Chung, Waihong et al. (2014) LRH1 promotes pancreatic cancer metastasis. Cancer Lett 350:15-24
Taylor, David L; Kutil, Nicholas J; Malek, Anna J et al. (2014) Mercury bioaccumulation in cartilaginous fishes from Southern New England coastal waters: contamination from a trophic ecology and human health perspective. Mar Environ Res 99:20-33
Motavallizadeh, Somayeh; Fallah-Tafti, Asal; Maleki, Saeedeh et al. (2014) Synthesis and evaluation of antiproliferative activity of substituted N-(9-oxo-9H-xanthen-4-yl)benzenesulfonamides. Tetrahedron Lett 55:373-375
Conicella, Alexander E; Fawzi, Nicolas L (2014) The C-terminal threonine of A?43 nucleates toxic aggregation via structural and dynamical changes in monomers and protofibrils. Biochemistry 53:3095-105
Hokeness, Kirsten; Kratch, Jacqueline; Nadolny, Christina et al. (2014) The effects of fungal volatile organic compounds on bone marrow stromal cells. Can J Microbiol 60:1-4

Showing the most recent 10 out of 51 publications