The University of Wyoming (UW) is a land-grant institution and the only baccalaureate, post-secondary degree granting institution in the State of Wyoming. This application is a continuation of the initial INBRE-1 award (P20 RR016474). The long-term programmatic goal to establish a statewide network for biomedical research excellence will be continued. With the recent hires of four new faculty who conduct research in the broad area of biomedical science, and a University commitment to support five additional hires during the next five years, the Wyoming INBRE Network is gradually acquiring a critical mass of biomedical research faculty needed to develop sustainable, competitive research programs. Consistent with the goal to build on past achievements and existing strengths, efforts will continue to focus on ways to provide opportunities for undergraduates across the Wyoming INBRE Network to participate in hands-on biomedical research. The three primary cores developed during INBRE-1 (Administrative, Bioinformatics, and Outreach) will be retained. Because of the success of the Outreach Core and its importance to the statewide network, this core will be expanded. Two thematic research areas have been identified based on existing strengths: 1) Cardiovascular Disease and 2) Obesity and Diabetes. These two thematic research areas are among the leading causes of morbidity, mortality and high health care costs in the US and are well within the scope of efforts for a healthy 21st century for Americans. The Wyoming INBRE Network will be enhanced by forming partnerships between faculty at UW and community colleges. This approach will provide role models to build links to other institutions and will be essential in moving the thematic research areas forward by increasing the quality and visibility of the research performed across the state. By creating opportunities for undergraduate and graduate students in biomedical research early in their academic careers, a pool of students will be created that will contribute to the next generation of health professionals, biomedical scientists and employees for the biotechnology industries. In addition, the Wyoming research network will be expanded across the western IDeA region as a joint effort among participants in the western regional IDeA programs

Public Health Relevance

This application is in response to PAR-08-150 and is designed to enhance biomedical research and education opportunities in the state of Wyoming by developing and maintaining the Wyoming IDeA Network of Biomedical Research Excellence (Wyoming INBRE). In addition to creating unique opportunities for faculty and students to succeed in biomedical research, a plan will be implemented to develop a pipeline of students for the next generation of biomedical scientists and health care specialists.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Exploratory Grants (P20)
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Special Emphasis Panel (ZRR1-RI-4 (01))
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Douthard, Regine
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University of Wyoming
Schools of Allied Health Profes
United States
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Chen, Zhilong; Song, Jiangping; Chen, Liang et al. (2018) Characterization of TTN Novex Splicing Variants across Species and the Role of RBM20 in Novex-Specific Exon Splicing. Genes (Basel) 9:
McAllister, Chris T; Motriuk-Smith, Dagmara; Kerr, Catherine M (2018) Three new coccidians (Cyclospora, Eimeria) from eastern moles, Scalopus aquaticus (Linnaeus) (Mammalia: Soricomorpha: Talpidae) from Arkansas, USA. Syst Parasitol 95:271-279
Guo, Wei; Sun, Mingming (2018) RBM20, a potential target for treatment of cardiomyopathy via titin isoform switching. Biophys Rev 10:15-25
Hull, Noah; Miller, Jonathan; Berry, David et al. (2018) Optimization of Brucella abortus Protocols for Downstream Molecular Applications. J Clin Microbiol 56:
Giri, Basant; Liu, Yukari; Nchocho, Fidelis N et al. (2018) Microfluidic ELISA employing an enzyme substrate and product species with similar detection properties. Analyst 143:989-998
Jiang, Zhongliang; Jiang, Kun; McBride, Ralph et al. (2018) Comparative cytocompatibility of multiple candidate cell types to photoencapsulation in PEGNB/PEGDA macroscale or microscale hydrogels. Biomed Mater 13:065012
Chen, Zhilong; Maimaiti, Rexiati; Zhu, Chaoqun et al. (2018) Z-band and M-band titin splicing and regulation by RNA binding motif 20 in striated muscles. J Cell Biochem 119:9986-9996
Guo, Rui; Hua, Yinan; Ren, Jun et al. (2018) Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity. Cell Death Dis 9:692
Geisler, Christoph (2018) A new approach for detecting adventitious viruses shows Sf-rhabdovirus-negative Sf-RVN cells are suitable for safe biologicals production. BMC Biotechnol 18:8
Kapp, Kirsten J; Yeatman, Ellen (2018) Microplastic hotspots in the Snake and Lower Columbia rivers: A journey from the Greater Yellowstone Ecosystem to the Pacific Ocean. Environ Pollut 241:1082-1090

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