The Bioinformatics Core (BC) works with the WV-INBRE Genomics Core (GC) at Marshall University (MU) and West Virginia University (WVU) GC to deliver integrated analysis of Next Generation Sequencing (NGS) and microarray data sets. NGS and microarray data analysis are and will be provided to network investigators as a full service from planning and experimental design, through DNA/RNA Quality Control (QC), wet lab experimentation with Quality Analysis (QA), data analysis and interpretation, to delivery of results, and discussion of their significance and additional methods of analysis. Under our service model, investigators must meet with BC and GC staff to discuss experimental design, methods of analysis, expected outcomes and costs prior to the initiation of any experimentation (full description of service plan is provided under section 11(3)). A separate description of the GC as an optional Core is provided as part of this application. Members of the BC and the GC work together on most of these services.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Exploratory Grants (P20)
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Special Emphasis Panel (ZGM1-TWD-7 (IN))
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Marshall University
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Racine, Christopher; Ward, Dakota; Anestis, Dianne K et al. (2014) 3,4,5-Trichloroaniline nephrotoxicity in vitro: potential role of free radicals and renal biotransformation. Int J Mol Sci 15:20900-12
Magro, Albert; Magro, Alice; Shrestha, Sirish et al. (2014) Metalloproteinase dependent reduction of cell surface cluster determinants upon the induction of apoptosis. Int J Oncol 44:1539-50
Tomblin, Justin K; Salisbury, Travis B (2014) Insulin like growth factor 2 regulation of aryl hydrocarbon receptor in MCF-7 breast cancer cells. Biochem Biophys Res Commun 443:1092-6
Rottgen, Trey S; Fancher, Ibra S; Asano, Shinichi et al. (2014) Bisphenol A activates BK channels through effects on * and *1 subunits. Channels (Austin) 8:249-57
Luanpitpong, Sudjit; Wang, Liying; Stueckle, Todd A et al. (2014) Caveolin-1 regulates lung cancer stem-like cell induction and p53 inactivation in carbon nanotube-driven tumorigenesis. Oncotarget 5:3541-54
Wenger, Sharon L; Hansroth, Joseph; Shackelford, Amy L (2014) Decreased telomere length in metaphase and interphase cells from newborns with trisomy 21. Gene 542:87
de Regt, Anna K; Yin, Yeshi; Withers, T Ryan et al. (2014) Overexpression of CupB5 activates alginate overproduction in Pseudomonas aeruginosa by a novel AlgW-dependent mechanism. Mol Microbiol 93:415-25
Withers, T Ryan; Yin, Yeshi; Yu, Hongwei D (2014) Identification and characterization of a novel inhibitor of alginate overproduction in Pseudomonas aeruginosa. Pathog Dis 70:185-8
Withers, T Ryan; Yin, Yeshi; Yu, Hongwei D (2014) Identification of novel genes associated with alginate production in Pseudomonas aeruginosa using mini-himar1 mariner transposon-mediated mutagenesis. J Vis Exp :
Valentovic, Monica A; Ball, John G; Brown, J Mike et al. (2014) Resveratrol attenuates cisplatin renal cortical cytotoxicity by modifying oxidative stress. Toxicol In Vitro 28:248-57

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