South Dakota Biomedical Research Infrastructure Network (SD BRIN), hosted by Sanford School of Medicine of University of South Dakota (USD SSOM) in Vermillion, SD, is the SD component of IDeA Networks of Biomedical Research Excellence (INBRE) program funded by NIH/NCRR Institutional Development Award (IDeA) program. This Phase II proposal for INBRE evolved from insights gained and enhancements made during Phase I of INBRE. Two main goals for SD INBRE Phase II are extensions of the same goals which provided a focus for Phase I. SD BRIN envisions a robust interdisciplinary collaborative network within SD to enhance basic biomedical research capabilities in cell biology and control of cell growth. This vision emphasizes proteomics and genomics at the host institution and predominantly undergraduate institutional (PUI) partners. Phase II goals for INBRE in SD are to: 1) Develop research capacity of SD in cell biology and the control of cell growth with emphasis on proteomics and genomics by: a) enhancing research capacity and critical mass of investigators in proteomics and genomics via mentoring of junior faculty members, b) maintaining professionally staffed proteomics, genomics, bioinformatics, and DNA sequencing and genotyping core facilities for investigators throughout S.D. (and other IDeA states), and c) providing increased graduate training and research support in basic biomedical sciences and bioinformatics. 2) Develop human resources for undergraduate and graduate programs in the biomedical sciences and bioinformatics , instill a culture of research, and provide a pipeline for students interested in biomedical research at South Dakota's predominantly undergraduate institutions and tribal colleges by: a) providing research support and mentoring for junior investigators and faculty from participating institutions, b) providing opportunities for, and understanding of, cutting-edge scientific research for students at participating institutions, c) introducing undergraduates to graduate programs and future careers in biomedical sciences and bioinformatics, and d) enhancing science education and research capabilities at tribal colleges, providing opportunities for further education and careers in science and research.

Public Health Relevance

SD BRIN is developing and supporting a state-wide interdisciplinary network infrastructure for biomedical research by partnering with predominantly undergraduate institutions and by funding core resources at the host institution. Faculty and students throughout SD are supported in planning and conducting biomedical research.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM103443-13
Application #
8499382
Study Section
Special Emphasis Panel (ZRR1-RI-4 (01))
Program Officer
Caldwell, Sheila
Project Start
2001-09-24
Project End
2014-04-30
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
13
Fiscal Year
2013
Total Cost
$3,044,801
Indirect Cost
$398,813
Name
University of South Dakota
Department
Other Basic Sciences
Type
Schools of Medicine
DUNS #
929930808
City
Vermillion
State
SD
Country
United States
Zip Code
57069
Bosch, T J; Hanna, T; Fercho, K A et al. (2018) Behavioral performance and visual strategies during skill acquisition using a novel tool use motor learning task. Sci Rep 8:13755
Anderson, Ruthellen H; Lensing, Cody J; Forred, Benjamin J et al. (2018) Differentiating Antiproliferative and Chemopreventive Modes of Activity for Electron-Deficient Aryl Isothiocyanates against Human MCF-7 Cells. ChemMedChem 13:1695-1710
Klonoski, Joshua M; Watson, Trevor; Bickett, Thomas E et al. (2018) Contributions of Influenza Virus Hemagglutinin and Host Immune Responses Toward the Severity of Influenza Virus: Streptococcus pyogenes Superinfections. Viral Immunol 31:457-469
Dosch, John; Hadley, Elise; Wiese, Cal et al. (2018) Time-lapse microscopic observation of non-dividing cells in cultured human osteosarcoma MG-63 cell line. Cell Cycle 17:174-181
Liang, Ashley Paula; Drazick, Anthony Thomas; Gao, Hongbo et al. (2018) Skeletal muscle secretion of IL-6 is muscle type specific: Ex vivo evidence. Biochem Biophys Res Commun 505:146-150
Herrera, Andrea L; Faal, Haddy; Moss, Danielle et al. (2018) The Streptococcus pyogenes fibronectin/tenascin-binding protein PrtF.2 contributes to virulence in an influenza superinfection. Sci Rep 8:12126
Messerli, Shanta M; Hoffman, Mariah M; Gnimpieba, Etienne Z et al. (2017) Therapeutic Targeting of PTK7 is Cytotoxic in Atypical Teratoid Rhabdoid Tumors. Mol Cancer Res 15:973-983
Messerli, Shanta M; Hoffman, Mariah M; Gnimpieba, Etienne Z et al. (2017) 4SC-202 as a Potential Treatment for the Pediatric Brain Tumor Medulloblastoma. Brain Sci 7:
Wegehaupt, Abby K; Roufs, Ellen K; Hewitt, Cory R et al. (2017) Recovery and assessment of leukocytes from LR Express filters. Biologicals 49:15-22
Oleas, Gabriela; Callegari, Eduardo; Sepúlveda, Romina et al. (2017) Heterologous expression, purification and characterization of three novel esterases secreted by the lignocellulolytic fungus Penicillium purpurogenum when grown on sugar beet pulp. Carbohydr Res 443-444:42-48

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