The new SC INBRE will build upon the solid foundation established during the current funding period, when all four SC INBRE Predominantly Undergraduate Institutions (PUIs: Claflin University, the College of Charleston, Furman and Winthrop Universities) have dramatically increased their biomedical research capacity, establishing strong undergraduate research training programs and substantially increasing the number of students who are pursuing further training as Ph.D. students, medical students or health professionals. SC INBRE support of target faculty, coupled with strong institutional commitment, established a cadre of extramurally funded investigators who serve as research mentors to undergraduate students engaged in research in the summer, as well as throughout the academic year as an integral part of the undergraduate curriculum, and to graduate students. SC INBRE succeeded beyond expectations at the three Comprehensive Research Universities (CRUs) in the establishment of a collaborative network for Regenerative Medicine/Bioengineering, with the hiring of new faculty at all three institutions, the establishment of new Bioengineering undergraduate and graduate programs, and the development of outstanding collaborative research programs across all three institutions, with solid extramural funding. In addition, a number of collaborations have been already established across institutions, and between PUI and CRU investigators. In this second phase of SC INBRE, we have added three institutions to the network: Francis Marion University, South Carolina State University and USC Beaufort. These new members provide additional sites and resources for biomedical research training and infrastructure development, and augment our ability to attract minority students to scientific careers. We will support and foster emerging. collaborations among member institutions, to increase the networking features of SC INBRE. We will build upon the strong foundation provided by the current SC INBRE to develop the CRU's Regenerative Medicine/ Bioengineering research in translational directions, and to coordinate CRU programs with research and training programs at the PUIs. We will intensify and focus our efforts to further build and support the pipeline for training, with particular attention to the recruitment and retention of minorities in biomedical science.
SC INBRE greatly Impacted the biomedical research infrastructure of the entire state of South Carolina, with effects that range from increased research training activities at the undergraduate and graduate level, to increased research funding, to widespread and unprecedented collaborations across institutions that greatly augmented these institutions'research and training capacity, and their competitiveness for research funds.
|Olsen, Anne C K; Triblehorn, Jeffrey D (2014) Neural responses from the filiform receptor neuron afferents of the wind-sensitive cercal system in three cockroach species. J Insect Physiol 68:76-86|
|Bradley, Amber; Zheng, Hui; Ziebarth, Angela et al. (2014) EDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer. Carcinogenesis 35:1100-9|
|Branham-O'Connor, Melissa; Robichaux 3rd, William G; Zhang, Xian-Kui et al. (2014) Defective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3). J Biol Chem 289:10738-47|
|Ghatak, Shibnath; Bogatkevich, Galina S; Atnelishvili, Ilia et al. (2014) Overexpression of c-Met and CD44v6 receptors contributes to autocrine TGF-?1 signaling in interstitial lung disease. J Biol Chem 289:7856-72|
|Xu, Hanwen; Zhang, Yu; Altomare, Diego et al. (2014) Six1 promotes epithelial-mesenchymal transition and malignant conversion in human papillomavirus type 16-immortalized human keratinocytes. Carcinogenesis 35:1379-88|
|Ghatak, Shibnath; Vyas, Alok; Misra, Suniti et al. (2014) Novel di-tertiary-butyl phenylhydrazones as dual cyclooxygenase-2/5-lipoxygenase inhibitors: synthesis, COX/LOX inhibition, molecular modeling, and insights into their cytotoxicities. Bioorg Med Chem Lett 24:317-24|
|Ghatak, Shibnath; Misra, Suniti; Norris, Russell A et al. (2014) Periostin induces intracellular cross-talk between kinases and hyaluronan in atrioventricular valvulogenesis. J Biol Chem 289:8545-61|
|DeRocher, Megan M; Armaly, Faris H; Lepore, Cara J et al. (2014) Rem2 in the bullfrog (Rana catesbeiana): Patterns of expression within the central nervous system and brain expression at different ontogenetic stages. Gene 540:37-45|
|McGorry, Clare A; Newman, Caroline N; Triblehorn, Jeffrey D (2014) Neural responses from the wind-sensitive interneuron population in four cockroach species. J Insect Physiol 66:59-70|
|Moore, Thomas; Chen, Hongyu; Morrison, Rachel et al. (2014) Nanotechnologies for noninvasive measurement of drug release. Mol Pharm 11:24-39|
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