The new SC INBRE will build upon the solid foundation established during the current funding period, when all four SC INBRE Predominantly Undergraduate Institutions (PUIs: Claflin University, the College of Charleston, Furman and Winthrop Universities) have dramatically increased their biomedical research capacity, establishing strong undergraduate research training programs and substantially increasing the number of students who are pursuing further training as Ph.D. students, medical students or health professionals. SC INBRE support of target faculty, coupled with strong institutional commitment, established a cadre of extramurally funded investigators who serve as research mentors to undergraduate students engaged in research in the summer, as well as throughout the academic year as an integral part of the undergraduate curriculum, and to graduate students. SC INBRE succeeded beyond expectations at the three Comprehensive Research Universities (CRUs) in the establishment of a collaborative network for Regenerative Medicine/Bioengineering, with the hiring of new faculty at all three institutions, the establishment of new Bioengineering undergraduate and graduate programs, and the development of outstanding collaborative research programs across all three institutions, with solid extramural funding. In addition, a number of collaborations have been already established across institutions, and between PUI and CRU investigators. In this second phase of SC INBRE, we have added three institutions to the network: Francis Marion University, South Carolina State University and USC Beaufort. These new members provide additional sites and resources for biomedical research training and infrastructure development, and augment our ability to attract minority students to scientific careers. We will support and foster emerging. collaborations among member institutions, to increase the networking features of SC INBRE. We will build upon the strong foundation provided by the current SC INBRE to develop the CRU's Regenerative Medicine/ Bioengineering research in translational directions, and to coordinate CRU programs with research and training programs at the PUIs. We will intensify and focus our efforts to further build and support the pipeline for training, with particular attention to the recruitment and retention of minorities in biomedical science.

Public Health Relevance

SC INBRE greatly Impacted the biomedical research infrastructure of the entire state of South Carolina, with effects that range from increased research training activities at the undergraduate and graduate level, to increased research funding, to widespread and unprecedented collaborations across institutions that greatly augmented these institutions'research and training capacity, and their competitiveness for research funds.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM103499-14
Application #
8717685
Study Section
Special Emphasis Panel (ZRR1)
Program Officer
Arora, Krishan
Project Start
2001-09-30
Project End
2015-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
14
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of South Carolina at Columbia
Department
Pathology
Type
Schools of Medicine
DUNS #
City
Columbia
State
SC
Country
United States
Zip Code
29208
Downs, Anna G; Scholles, Katie R; Hollis, David M (2016) Localization of rem2 in the central nervous system of the adult rainbow trout (Oncorhynchus mykiss). J Chem Neuroanat 78:87-95
Prim, David A; Zhou, Boran; Hartstone-Rose, Adam et al. (2016) A mechanical argument for the differential performance of coronary artery grafts. J Mech Behav Biomed Mater 54:93-105
Doe, David A; Smith 3rd, Julian P S (2016) Structure of the male copulatory apparatus in Prognathorhynchus busheki (Platyhelminthes, Kalyptorhynchia). Invertebr Biol 135:150-162
Tomar, Swati; Graves, Christian A; Altomare, Diego et al. (2016) Human papillomavirus status and gene expression profiles of oropharyngeal and oral cancers from European American and African American patients. Head Neck 38 Suppl 1:E694-704
Pawelek, Kasia A; Dor Jr, Daniel; Salmeron, Cristian et al. (2016) Within-Host Models of High and Low Pathogenic Influenza Virus Infections: The Role of Macrophages. PLoS One 11:e0150568
Sanchez, Enis; Lu, Steven; Reed, Carson et al. (2016) Kemp Elimination in Cationic Micelles: Designed Enzyme-Like Rates Achieved through the Addition of Long-Chain Bases. J Phys Org Chem 29:185-189
Lang, Hainan; Nishimoto, Eishi; Xing, Yazhi et al. (2016) Contributions of Mouse and Human Hematopoietic Cells to Remodeling of the Adult Auditory Nerve After Neuron Loss. Mol Ther 24:2000-2011
McShane, Ariel; Hok, Eveline; Tomberlin, Jensen et al. (2016) The Enzymatic Paradox of Yeast Arginyl-tRNA Synthetase: Exclusive Arginine Transfer Controlled by a Flexible Mechanism of tRNA Recognition. PLoS One 11:e0148460
Bao, Weier; Greenwold, Matthew J; Sawyer, Roger H (2016) Expressed miRNAs target feather related mRNAs involved in cell signaling, cell adhesion and structure during chicken epidermal development. Gene 591:393-402
Hatkevich, Talia; Kohl, Kathryn P; McMahan, Susan et al. (2016) Bloom Syndrome Helicase Promotes Meiotic Crossover Patterning and Homolog Disjunction. Curr Biol :

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