Abstract

The Administrative Core will serve as the centralized coordinating resource for the Oklahoma Developmental Biology COBRE. The Core Director will facilitate communication among the Oklahoma Junior Investigator and Pilot Project developmental biologists and their Mentors, ensure compliance with all NIH policies, and provide a foundation for scientific growth in basic and translational Developmental Biology research. The Administrative Core Director will be the primary contact for the Network of COBREs and the NIH. To accomplish these goals, the Administrative Core will focus on the following Specific Aims:
Aim 1. To provide central management for the Oklahoma Developmental Biology COBRE components and activities.
Aim 2. To provide mentoring for the Junior Investigators and assist with their transition to fully independent status.
Aim 3. To administer the Pilot Project Program.
Aim 4. To promote multidisciplinary approaches to research and interactions among the COBRE investigators through a vigorous monthly seminar program.
Aim 5. To facilitate interactions of the Oklahoma Developmental Biology COBRE with other COBREs and with the national program.
Aim 6. To provide fiscal management of the COBRE and compliance with regulatory issues.
Aim 7. To promote data sharing strategies.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM103636-05
Application #
9234548
Study Section
Special Emphasis Panel (ZGM1-TWD-B)
Project Start
Project End
2018-08-31
Budget Start
2017-03-01
Budget End
2018-02-28
Support Year
5
Fiscal Year
2017
Total Cost
$249,481
Indirect Cost
$100,981

  Institution

Name
Oklahoma Medical Research Foundation
Department
Type
Research Institutes
DUNS #
077333797
City
Oklahoma City
State
OK
Country
United States
Zip Code
73104

  Publications

Bhaskaran, Shylesh; Pharaoh, Gavin; Ranjit, Rojina et al. (2018) Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance. EMBO Rep 19:
Siefert, Joseph C; Clowdus, Emily A; Goins, Duane et al. (2018) Profiling DNA Replication Timing Using Zebrafish as an In Vivo Model System. J Vis Exp :
Borga, Chiara; Park, Gilseung; Foster, Clay et al. (2018) Simultaneous B and T cell acute lymphoblastic leukemias in zebrafish driven by transgenic MYC: implications for oncogenesis and lymphopoiesis. Leukemia :
Wren, Jonathan D (2018) Algorithmically outsourcing the detection of statistical errors and other problems. EMBO J 37:
Georgescu, Constantin; Wren, Jonathan D (2018) Algorithmic identification of discrepancies between published ratios and their reported confidence intervals and P-values. Bioinformatics 34:1758-1766
Snider, Timothy A; Richardson, Arlan; Stoner, Julie A et al. (2018) The Geropathology Grading Platform demonstrates that mice null for Cu/Zn-superoxide dismutase show accelerated biological aging. Geroscience 40:97-103
Sansam, Courtney G; Pietrzak, Katarzyna; Majchrzycka, Blanka et al. (2018) A mechanism for epigenetic control of DNA replication. Genes Dev 32:224-229
Sun, Chengyi; Berry, William L; Olson, Lorin E (2017) PDGFR? controls the balance of stromal and adipogenic cells during adipose tissue organogenesis. Development 144:83-94
Tipton, Aaron R; Wren, Jonathan D; Daum, John R et al. (2017) GTSE1 regulates spindle microtubule dynamics to control Aurora B kinase and Kif4A chromokinesin on chromosome arms. J Cell Biol 216:3117-3132
Siefert, Joseph C; Georgescu, Constantin; Wren, Jonathan D et al. (2017) DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation. Genome Res 27:1406-1416

Showing the most recent 10 out of 57 publications