This proposal is to create a Center of Biomedical Research Excellence (COBRE) in Integrative Neuroscience at the University of Nevada, Reno (UNR). Research in the neurosciences is proceeding on many fronts and addressing fundamental questions in both basic and clinical science.
The aim of this COBRE is to establish a research center that can promote interdisciplinary interactions and investigations of neural function, impairments, and repair, by bridging and cross-fertilizing several research units at UNR that have already developed teams of focused expertise in neuroscience, from molecular to behavioral and from understanding normal structure and function to neurological deficits and their treatment. The center will span 3 different colleges and the Medical School, and will support projects led by 5 highly accomplished junior faculty drawn from the departments of Psychology, Biology, Biomedical Engineering, and Physiology and Cell Biology. The research and professional development of these faculty will be mentored by a strong team of successful researchers who will also bring perspectives and expertise drawn from many disciplines. The center will also provide the infrastructure to support the projects as well as new research opportunities throughout the institution by establishing two new core facilities. One core will support training, use, and analysis of structural and functional magnetic resonance imaging (MRl). This core will provide - for the first time - access at UNR to the now standard research tools provided by MRl. The second core will support investigations directed at different patient populations by developing a database that will allow researchers to identify and recruit participants with well defined neurological lesions. Both the center and new core facilities will expand research strengths and translational neuroscience at UNR in entirely new directions, while providing infrastructure that has broad applications in both basic and clinical research and can thus support use and research synergisms across many disciplines and programs on campus and in the state.

Public Health Relevance

Neurological impairments and disease are a major focus of healthcare, and understanding and treating these impairments is central to the mission of many institutes at NIH. The COBRE will support research that will help to characterize both the healthy brain and neural disorders, and will advance knowledge ranging from the neural basis of behavior to neural damage and repair.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Exploratory Grants (P20)
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Special Emphasis Panel (ZRR1-RI-4 (01))
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Gorospe, Rafael
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University of Nevada Reno
Schools of Arts and Sciences
United States
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Vercillo, Tiziana; Jiang, Fang (2017) Spatial modulation of motor-sensory recalibration in early deaf individuals. Neuropsychologia 102:39-44
Yang, Wen-Yan; Tang, Xiao-Tian; Ju, Rui-Ting et al. (2017) The population genetic structure of Corythucha ciliata (Say) (Hemiptera: Tingidae) provides insights into its distribution and invasiveness. Sci Rep 7:635
Downing, Laura E; Ferguson, Bradley S; Rodriguez, Kelvin et al. (2017) A grape seed procyanidin extract inhibits HDAC activity leading to increased Ppar? phosphorylation and target-gene expression. Mol Nutr Food Res 61:
Vercillo, Tiziana; Carrasco, Carlos; Jiang, Fang (2017) Age-Related Changes in Sensorimotor Temporal Binding. Front Hum Neurosci 11:500
Stephens, Jaclyn A; Jones, Kevin T; Berryhill, Marian E (2017) Task demands, tDCS intensity, and the COMT val158met polymorphism impact tDCS-linked working memory training gains. Sci Rep 7:13463
Chen, Siqi; Zaeimian, Masoumeh Saber; Monteiro, Jorge H S K et al. (2017) Mn Doped AIZS/ZnS Nanocrystals: Synthesis and Optical Properties. J Alloys Compd 725:1077-1083
Strother, Lars; Zhou, Zhiheng; Coros, Alexandra K et al. (2017) An fMRI study of visual hemifield integration and cerebral lateralization. Neuropsychologia 100:35-43
Zhou, Zhiheng; Strother, Lars (2017) Distinct effects of contour smoothness and observer bias on visual persistence. J Vis 17:8
Kim, Minkyung; Fontelonga, Tatiana M; Lee, Clare H et al. (2017) Motor axons are guided to exit points in the spinal cord by Slit and Netrin signals. Dev Biol 432:178-191
Gomez, Michael A; Snow, Jacqueline C (2017) Action properties of object images facilitate visual search. J Exp Psychol Hum Percept Perform 43:1115-1124

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