We request funds to establish a COBRE brain-lesioned patient database core facility. The brain-lesioned patient database will interface with local clinicians and organizations to identify/enroll individuals with brainlesions (e.g. stroke, resection) or other relevant conditions (e.g. autism). The brain-lesioned patient database core will expand to accommodate demand for different brain-lesioned patient groups. The establishment of the brain-lesioned patient database core will fill a major gap in cognitive neuroscience research needs at UNR. This core will directly support Projects 1 (Berryhill) and 2 (Caplovitz). Here, we are building infrastructure for use by researchers from the Psychology, particularly Clinical Psychology, and Biology Departments, and at the Medical School. The core will be located at UNR in Northern Nevada, an area with large Hispanic and Native American communities, and a large underserved rural population. The presence of a brain-lesioned patient database will make research in brain-lesioned populations possible by reducing the administrative and logistical challenges of assembling patient cohorts. Furthermore, the brain-lesioned patient database will be designed by the Nevada INBRE: Bioinformatics Core. The long-term goal will be to interface with other brain-lesioned database centers, such as UC Davis and to extend coverage throughout Nevada. The state of Nevada has a potentially large, untapped brain-lesioned patient population that is currently impossible for Nevada researchers to adequately study because this type of core resource does not exist. This will allow for the accumulation of rare and diverse patient populations to advance our understanding ofthe brain and facilitate research and treatment. The brain-lesioned patient database will be housed in Mack Social Science (MSS 411). This core will be directed by Jeffrey Hutsler (Assistant Professor, Department of Psychology, located in MSS 414). A database manager (TBN) will be hired from COBRE funding. Under Dr. Hutsler's supervision, the database manager will conduct neuropsychological screening tests and will schedule testing sessions.

Public Health Relevance

The brain-lesioned patient database will support research in special populations from COBRE projects and other researchers with translational or special-population based research questions. COBRE researchers will directly benefit from the establishment of the brain-lesioned patient database.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Exploratory Grants (P20)
Project #
Application #
Study Section
Special Emphasis Panel (ZRR1-RI-4)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Nevada Reno
United States
Zip Code
Skiba, Rafal M; Snow, Jacqueline C (2016) Attentional capture for tool images is driven by the head end of the tool, not the handle. Atten Percept Psychophys 78:2500-2514
Erlikhman, Gennady; Caplovitz, Gideon P (2016) Decoding information about dynamically occluded objects in visual cortex. Neuroimage :
Moreno-Bravo, Juan A; Martinez-Lopez, Jesus E; Madrigal, M Pilar et al. (2016) Developmental guidance of the retroflex tract at its bending point involves Robo1-Slit2-mediated floor plate repulsion. Brain Struct Funct 221:665-78
Gruner, Hannah; Cortés-López, Mariela; Cooper, Daphne A et al. (2016) CircRNA accumulation in the aging mouse brain. Sci Rep 6:38907
Stephens, Jaclyn A; Berryhill, Marian E (2016) Older Adults Improve on Everyday Tasks after Working Memory Training and Neurostimulation. Brain Stimul 9:553-9
Zhang, Yong; Lamba, Pallavi; Guo, Peiyi et al. (2016) miR-124 Regulates the Phase of Drosophila Circadian Locomotor Behavior. J Neurosci 36:2007-13
Erlikhman, Gennady; Gurariy, Gennadiy; Mruczek, Ryan E B et al. (2016) The neural representation of objects formed through the spatiotemporal integration of visual transients. Neuroimage 142:67-78
Downing, Laura E; Ferguson, Bradley S; Rodriguez, Kelvin et al. (2016) A grape seed procyanidin extract inhibits HDAC activity leading to increased Pparα phosphorylation and target-gene expression. Mol Nutr Food Res :
Kim, Kyung-Tai; Kim, Namhee; Kim, Hwan-Ki et al. (2016) ISL1-based LIM complexes control Slit2 transcription in developing cranial motor neurons. Sci Rep 6:36491
Bjorke, Brielle; Shoja-Taheri, Farnaz; Kim, Minkyung et al. (2016) Contralateral migration of oculomotor neurons is regulated by Slit/Robo signaling. Neural Dev 11:18

Showing the most recent 10 out of 62 publications