This Core integrates and enhances the capabilities of two existing scientific cores at KUMC: the Electron Microscope Research Laboratory (EMRL) and the Confocal Imaging Facility (CIF), both of which have assisted investigators at KUMC for many years. The High Resolution Imaging Core will provide cost effective and time-saving services for the preparation and viewing of samples by routine confocal and scanning and transmission electron microscope imaging. More than 20% of the senior faculty and all of the COBRE Beginning Investigators have steady needs for high resolution microscopy. This Core will offer new, expanded service carried out by expert technicians that will include immunolocalization technology for both light and electron microscopy.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
5P20GM104936-07
Application #
8534218
Study Section
Special Emphasis Panel (ZRR1-RI-B)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
7
Fiscal Year
2013
Total Cost
$116,034
Indirect Cost
$39,191
Name
University of Kansas
Department
Type
DUNS #
016060860
City
Kansas City
State
KS
Country
United States
Zip Code
66160
Tran, Pamela V; Sharma, Madhulika; Li, Xiaogang et al. (2014) Developmental signaling: does it bridge the gap between cilia dysfunction and renal cystogenesis? Birth Defects Res C Embryo Today 102:159-73
Cha, Jeeyeon; Bartos, Amanda; Park, Craig et al. (2014) Appropriate crypt formation in the uterus for embryo homing and implantation requires Wnt5a-ROR signaling. Cell Rep 8:382-92
Pierce, A N; Ryals, J M; Wang, R et al. (2014) Vaginal hypersensitivity and hypothalamic-pituitary-adrenal axis dysfunction as a result of neonatal maternal separation in female mice. Neuroscience 263:216-30
Kumar, T Rajendra (2014) The quest for male germline stem cell markers: PAX7 gets ID'd. J Clin Invest 124:4219-22
Rumi, M A Karim; Dhakal, Pramod; Kubota, Kaiyu et al. (2014) Generation of Esr1-knockout rats using zinc finger nuclease-mediated genome editing. Endocrinology 155:1991-9
Tan, Ee Phie; Villar, Maria T; E, Lezi et al. (2014) Altering O-linked ?-N-acetylglucosamine cycling disrupts mitochondrial function. J Biol Chem 289:14719-30
Saadi, Irfan; Das, Pragnya; Zhao, Minglian et al. (2013) Msx1 and Tbx2 antagonistically regulate Bmp4 expression during the bud-to-cap stage transition in tooth development. Development 140:2697-702
Dasouki, Majed J; Rafi, Syed K; Olm-Shipman, Adam J et al. (2013) Exome sequencing reveals a thrombopoietin ligand mutation in a Micronesian family with autosomal recessive aplastic anemia. Blood 122:3440-9
Taniguchi, Cullen M; Finger, Elizabeth C; Krieg, Adam J et al. (2013) Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes. Nat Med 19:1325-30
Abrahamson, Dale R; St John, Patricia L; Stroganova, Larysa et al. (2013) Laminin and type IV collagen isoform substitutions occur in temporally and spatially distinct patterns in developing kidney glomerular basement membranes. J Histochem Cytochem 61:706-18

Showing the most recent 10 out of 11 publications