(Administrative Core) The long-term objectives of this COBRE application are to promote and increase clinical, translational and implementation research in cardiometabolic diseases at Tulane University by establishing a Center of Excellence for Clinical, Translational and Implementation Research in Cardiometabolic Diseases; developing and nurturing successful competitive independent investigators engaged in clinical, translational and implementation research; motivating and facilitating multidisciplinary and interdisciplinary interaction and collaboration in the area of cardiometabolic disease research among basic, clinical, and population scientists; and building and expanding the clinical and community-based research infrastructure at Tulane University and in Louisiana. The overall objective of the Administrative Core is to provide administrative, fiscal, and scientific support to junior faculty investigators, senior faculty mentors, research core facilities, and collaborative researchers; and to ensure good management, integration, and oversight of the proposed COBRE program.
The specific aims of the administrative core are: 1. to provide skilled personnel for effective fiscal and administrative management of all components of the COBRE program; 2. to provide vision and mentorship to each junior faculty investigator in relation to their research project and career development by senior faculty mentors and the COBRE Program Director; 3. to organize multidisciplinary seminars and research in progress meetings and facilitate interaction and collaboration among investigators; 4. to conduct formative and summative evaluation of junior faculty investigators with members of the Internal and External Advisory Committees with specific milestones on: a) progress of the research project, b) peer-reviewed presentations and publications, and c) preparation and submission of an R01 grant application. Constructive plans for effective approaches to resolve weaknesses will be presented to junior faculty investigators and their mentors; 5. to coordinate and support pre- and post-doctoral training programs in clinical, translational and implementation research; 6. to evaluate the outcomes and success of our tailored team-mentoring plan and the COBRE program; 7. to develop and implement the vision and long-term goals of the Tulane Center of Excellence for Clinical, Translational and Implementation Research in Cardiometabolic Diseases; and 8. to coordinate the communication and interaction with NIGMS program staff for optimal achievement of program development and long-term goals of this COBRE program. The Administrative Core will provide leadership and administrative support to junior faculty investigators and their individual research projects. The Administrative Core will play a critically important role in the development of junior faculty investigators and their transition to and attainment of successful competitive independent investigator status. The Administrative Core will also play an important role in establishing and maintaining an internationally recognized clinical, translational, and implementation research program in the etiology, prevention, and treatment of cardiometabolic diseases.

Public Health Relevance

(Administrative Core) The overall objective of the Administrative Core is to provide administrative, fiscal, and scientific support to junior faculty investigators, senior faculty mentors, research core facilities, and collaborative researchers; and to ensure good management, integration, and oversight of the proposed COBRE program. The Administrative Core will play a critically important role in the development of junior faculty investigators and their transition to and attainment of independent investigator status and in establishing and maintaining an internationally recognized clinical, translational, and implementation research program in the etiology, prevention, and treatment of cardiometabolic diseases.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
1P20GM109036-01A1
Application #
8813112
Study Section
Special Emphasis Panel (ZGM1-TWD-6 (C1))
Project Start
Project End
Budget Start
2014-12-01
Budget End
2015-11-30
Support Year
1
Fiscal Year
2016
Total Cost
$454,504
Indirect Cost
$152,508
Name
Tulane University
Department
Type
DUNS #
053785812
City
New Orleans
State
LA
Country
United States
Zip Code
70118
Ku, Elaine; Kopple, Joel D; Johansen, Kirsten L et al. (2018) Longitudinal Weight Change During CKD Progression and Its Association With Subsequent Mortality. Am J Kidney Dis 71:657-665
Bundy, Joshua D; Bazzano, Lydia A; Xie, Dawei et al. (2018) Self-Reported Tobacco, Alcohol, and Illicit Drug Use and Progression of Chronic Kidney Disease. Clin J Am Soc Nephrol 13:993-1001
Anderson, Christopher E; Hamm, L Lee; Batuman, Gem et al. (2018) The association of angiogenic factors and chronic kidney disease. BMC Nephrol 19:117
Zhou, Yu; Gao, Yunlong; Xu, Chao et al. (2018) A novel approach for correction of crosstalk effects in pathway analysis and its application in osteoporosis research. Sci Rep 8:668
Liu, Hui-Min; He, Jing-Yang; Zhang, Qiang et al. (2018) Improved detection of genetic loci in estimated glomerular filtration rate and type 2 diabetes using a pleiotropic cFDR method. Mol Genet Genomics 293:225-235
Liang, Xiao; Wu, CuiYan; Zhao, Hongmou et al. (2018) Assessing the genetic correlations between early growth parameters and bone mineral density: A polygenic risk score analysis. Bone 116:301-306
Yan, Yinkun; Zhang, Tao; Li, Shengxu et al. (2018) Black-White Difference in the Impact of Long-Term Blood Pressure From Childhood on Adult Renal Function: The Bogalusa Heart Study. Am J Hypertens 31:1300-1306
Liu, Li; Wen, Yan; Zhang, Lei et al. (2018) Assessing the Associations of Blood Metabolites With Osteoporosis: A Mendelian Randomization Study. J Clin Endocrinol Metab 103:1850-1855
Dorans, Kirsten S; Mills, Katherine T; Liu, Yang et al. (2018) Trends in Prevalence and Control of Hypertension According to the 2017 American College of Cardiology/American Heart Association (ACC/AHA) Guideline. J Am Heart Assoc 7:
Rice, Mary B; Li, Wenyuan; Dorans, Kirsten S et al. (2018) Exposure to Traffic Emissions and Fine Particulate Matter and Computed Tomography Measures of the Lung and Airways. Epidemiology 29:333-341

Showing the most recent 10 out of 86 publications