Abstract

Public Health Relevance

The mechanisms underiying the beneficial effects of rehabilitation and cortical stimulation are poorly understood, and preclinical studies can provide key biological data to understand and optimize these approaches. The findings of this work may reveal new vascular-based therapeutic targets for treatment of post-stroke disabilities.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
1P20GM109040-01
Application #
8663390
Study Section
Special Emphasis Panel (ZGM1-TWD-C (C1))
Project Start
2014-06-02
Project End
2019-03-31
Budget Start
2014-06-02
Budget End
2015-03-31
Support Year
1
Fiscal Year
2014
Total Cost
$192,588
Indirect Cost
$63,766

  Institution

Name
Medical University of South Carolina
Department
Type
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425

  Publications

Chhatbar, Pratik Y; Kautz, Steven A; Takacs, Istvan et al. (2018) Evidence of transcranial direct current stimulation-generated electric fields at subthalamic level in human brain in vivo. Brain Stimul 11:727-733
Wilmskoetter, Janina; Martin-Harris, Bonnie; Pearson Jr, William G et al. (2018) Differences in swallow physiology in patients with left and right hemispheric strokes. Physiol Behav 194:144-152
Berthiaume, Andrée-Anne; Grant, Roger I; McDowell, Konnor P et al. (2018) Dynamic Remodeling of Pericytes In Vivo Maintains Capillary Coverage in the Adult Mouse Brain. Cell Rep 22:8-16
Alawieh, Ali; Andersen, Meredith; Adkins, DeAnna L et al. (2018) Acute Complement Inhibition Potentiates Neurorehabilitation and Enhances tPA-Mediated Neuroprotection. J Neurosci 38:6527-6545
Alawieh, Ali; Langley, E Farris; Tomlinson, Stephen (2018) Targeted complement inhibition salvages stressed neurons and inhibits neuroinflammation after stroke in mice. Sci Transl Med 10:
Badran, Bashar W; Dowdle, Logan T; Mithoefer, Oliver J et al. (2018) Neurophysiologic effects of transcutaneous auricular vagus nerve stimulation (taVNS) via electrical stimulation of the tragus: A concurrent taVNS/fMRI study and review. Brain Stimul 11:492-500
Hartmann, David A; Hyacinth, Hyacinth I; Liao, Francesca-Fang et al. (2018) Does pathology of small venules contribute to cerebral microinfarcts and dementia? J Neurochem 144:517-526
Hanlon, Colleen A; Dowdle, Logan T; Henderson, J Scott (2018) Modulating Neural Circuits with Transcranial Magnetic Stimulation: Implications for Addiction Treatment Development. Pharmacol Rev 70:661-683
Aaron, Stacey E; Vanderwerker, Catherine J; Embry, Aaron E et al. (2018) FES-assisted Cycling Improves Aerobic Capacity and Locomotor Function Postcerebrovascular Accident. Med Sci Sports Exerc 50:400-406
VanDerwerker, Catherine J; Ross, Ryan E; Stimpson, Katy H et al. (2018) Combining therapeutic approaches: rTMS and aerobic exercise in post-stroke depression: a case series. Top Stroke Rehabil 25:61-67

Showing the most recent 10 out of 92 publications