The Administrative Core (ADMIN) is responsible for the leadership, integration and successful operations of the COBRE in Stroke Recovery. The PD/PI and Associate Director are assisted by an Executive Committee and Internal Advisory Committee as well as an External Advisory Board of 5 eminent scientists who provide objective oversight, peer review, evaluation and strategic interactions to optimize the Center?s impact. The ADMIN Core supports the effort of the Program Director (PD/PI), Mentors of 4 Phase II Junior Investigators, Director of a competitive peer-reviewed Pilot Project Program, and a team of experienced support personnel who handle fiscal management and reporting, scheduling, coordination of COBRE activities, evaluation activities, IT and communication/dissemination functions.
Aim 1 is to provide integrated fiscal and administrative management for all components of the program, including coordination of meetings, management of fiscal and personnel matters, oversight, accountability, enhanced website features, and dissemination of results.
Aim 2 is to enhance the ability of individual investigators to obtain peer-reviewed grants and establish long-term academic research careers in stroke recovery through intensive multiple source mentoring, access to core resources, and diversified opportunities for research support.
Aim 3 is to continue our successful Pilot Project Program in stroke recovery research.
Aim 4 is to provide scientific and programmatic leadership for success and sustainability via three sub- aims that address: a) strategic planning and implementation, b) increasing and diversifying the research portfolio, and c) promoting the finanical independence of the center, including appropriate cost recovery/reimbursement models for core services.
Aim 5 is to continue to evolve our integrated Evaluation Program, focusing on six long- term strategic goals developed during Phase I and implementing a full suite of metrics to guide infrastructure development, including a dashboard of key metrics. Innovative features of the COBRE?s conceptual and administrative structure include: a) a multidisciplinary leadership team that includes a PhD biomedical engineer/biomechanical scientist and an MD/clinical stroke expert, coalescing resources and disciplines from the Colleges of Health Professions and Medicine; b) our multiple source mentoring approach bringing multidisciplinary perspectives, expertise and tools to serve the Junior Investigators? development toward research independence; c) technological innovations fostered by frequent interactions of experts in diverse fields of brain biology, bioimaging and biomechanics; d) a Pilot Project Program using a novel web-based platform developed by MUSC?s CTSA (SCTR); and e) development of a dashboard of key metrics in infographic style for COBRE leadership to monitor progress and make program modifications as needed to strengthen the Center.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Exploratory Grants (P20)
Project #
2P20GM109040-06
Application #
9573496
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2019-04-01
Budget End
2020-03-31
Support Year
6
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Medical University of South Carolina
Department
Type
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29407
Aaron, Stacey E; Vanderwerker, Catherine J; Embry, Aaron E et al. (2018) FES-assisted Cycling Improves Aerobic Capacity and Locomotor Function Postcerebrovascular Accident. Med Sci Sports Exerc 50:400-406
VanDerwerker, Catherine J; Ross, Ryan E; Stimpson, Katy H et al. (2018) Combining therapeutic approaches: rTMS and aerobic exercise in post-stroke depression: a case series. Top Stroke Rehabil 25:61-67
Shih, Andy Y; Hyacinth, Hyacinth I; Hartmann, David A et al. (2018) Rodent Models of Cerebral Microinfarct and Microhemorrhage. Stroke 49:803-810
Wonsetler, Elizabeth C; Miller, Ellie L; Huey, Katherine L et al. (2018) Association Between Altered Hip Extension and Kinetic Gait Variables. Am J Phys Med Rehabil 97:131-133
Seamon, Bryant A; Neptune, Richard R; Kautz, Steven A (2018) Using a Module-Based Analysis Framework for Investigating Muscle Coordination during Walking in Individuals Poststroke: A Literature Review and Synthesis. Appl Bionics Biomech 2018:3795754
Badran, Bashar W; Mithoefer, Oliver J; Summer, Caroline E et al. (2018) Short trains of transcutaneous auricular vagus nerve stimulation (taVNS) have parameter-specific effects on heart rate. Brain Stimul 11:699-708
Charalambous, Charalambos C; Dean, Jesse C; Adkins, DeAnna L et al. (2018) Characterizing the corticomotor connectivity of the bilateral ankle muscles during rest and isometric contraction in healthy adults. J Electromyogr Kinesiol 41:9-18
Alawieh, Ali; Langley, E Farris; Weber, Shannon et al. (2018) Identifying the role of complement in triggering neuroinflammation after traumatic brain injury. J Neurosci :
Berthiaume, Andrée-Anne; Hartmann, David A; Majesky, Mark W et al. (2018) Pericyte Structural Remodeling in Cerebrovascular Health and Homeostasis. Front Aging Neurosci 10:210
Dowdle, Logan T; Brown, Truman R; George, Mark S et al. (2018) Single pulse TMS to the DLPFC, compared to a matched sham control, induces a direct, causal increase in caudate, cingulate, and thalamic BOLD signal. Brain Stimul 11:789-796

Showing the most recent 10 out of 92 publications