Slowing the rate of increase in type 2 diabetes nationally is one of the most urgent health problems we face. Worst affected are minority populations such as the Mexican American population along the US/Mexico border, where rates have doubled over the last two decades (now over 20% of all adults). Even in children we find rates much higher than nationally of overweight and other predictors of early onset type 2 diabetes. The rate of increase shows no sign of slowing. It is difficult, therefore, to overstate the urgency of addressing effective measures to prevent diabetes in minority populations. This proposal builds on the research opportunities established in the Hispanic Health Research Center of the Lower Rio Grande Valley through NCMHD Project EXPORT (MD000170 P20). This Center of Excellence application aims to 1) understand the changes proximal to the development of overt diabetes, 2) understand the mental health impact of diabetes and the potential for early intervention, 3) utilize the strong family unit in the Mexican American population to reduce the risk of obesity and diabetes in children through parental intervention, and 4) understand how to use the successful technique of behavioral journalism and the media to change diet and physical activity behavior at the population level. The scientific focus of the Center of Excellence is thus to conduct research on the physiologic progression to diabetes and its complications among Mexican Americans, and to develop diabetes prevention strategies and test innovative approaches to effective interventions in a minority population severely affected by type 2 diabetes. We intend our Center of Excellence to be a collaborative resource for diabetes and its complications in Mexican Americans providing critical cultural understanding and appropriate tools for epidemiological, intervention, and physiologic research. The proposed Center of Excellence on Diabetes in Americans of Mexican Descent proposes an administrative core, a research core including three research projects and two pilot studies, a training core and a community engagement core.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
5P20MD000170-10
Application #
8233945
Study Section
Special Emphasis Panel (ZRG1-DIG-B (52))
Program Officer
Tabor, Derrick C
Project Start
2003-03-03
Project End
2014-02-28
Budget Start
2012-03-01
Budget End
2014-02-28
Support Year
10
Fiscal Year
2012
Total Cost
$1,380,657
Indirect Cost
$409,437
Name
University of Texas Health Science Center Houston
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
800771594
City
Houston
State
TX
Country
United States
Zip Code
77225
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Garza, Ariana L; Vatcheva, Kristina P; Pan, Jen-Jung et al. (2016) Liver and Other Gastrointestinal Cancers Are Frequent in Mexican Americans. J Racial Ethn Health Disparities 3:1-10
Wu, Shenghui; Fisher-Hoch, Susan P; Reininger, Belinda et al. (2016) Recommended Levels of Physical Activity Are Associated with Reduced Risk of the Metabolic Syndrome in Mexican-Americans. PLoS One 11:e0152896
Olvera, R L; Fisher-Hoch, S P; Williamson, D E et al. (2016) Depression in Mexican Americans with diagnosed and undiagnosed diabetes. Psychol Med 46:637-46
Sanderson, Maureen; Khabele, Dineo; Brown, Claudine L et al. (2015) Results of a Health Education Message Intervention on HPV Knowledge and Receipt of Follow-up Care among Latinas Infected with High-risk Human Papillomavirus. J Health Care Poor Underserved 26:1440-55
Reininger, Belinda M; Wang, Jing; Fisher-Hoch, Susan P et al. (2015) Non-communicable diseases and preventive health behaviors: a comparison of Hispanics nationally and those living along the US-Mexico border. BMC Public Health 15:564
Gay, Jennifer L; Salinas, Jennifer J; Buchner, David M et al. (2015) Meeting physical activity guidelines is associated with lower allostatic load and inflammation in Mexican Americans. J Immigr Minor Health 17:574-81
Reininger, Belinda M; Mitchell-Bennett, Lisa; Lee, MinJae et al. (2015) Tu Salud, ¡Si Cuenta!: Exposure to a community-wide campaign and its associations with physical activity and fruit and vegetable consumption among individuals of Mexican descent. Soc Sci Med 143:98-106
Olvera, Rene L; Williamson, Douglas E; Fisher-Hoch, Susan P et al. (2015) Depression, obesity, and metabolic syndrome: prevalence and risks of comorbidity in a population-based representative sample of Mexican Americans. J Clin Psychiatry 76:e1300-5
Ranjit, Nalini; Wilkinson, Anna V; Lytle, Leslie M et al. (2015) Socioeconomic inequalities in children's diet: the role of the home food environment. Int J Behav Nutr Phys Act 12 Suppl 1:S4

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