The proposed Center of Excellence on Diabetes in Americans of Mexican Descent aims to conduct research on the physiologic progression to diabetes and its complications among Mexican Americans, and to develop diabetes prevention strategies and test innovative approaches to effective interventions in a minority population severely affected by type 2 diabetes. This Center proposes an administrative core, a research core including three research projects and two pilot studies, a training core and a community engagement core. As part of the research core, the South Texas Parent Diabetes Prevention Trial (STPDPT) aims to test the effectiveness of a brief motivational enhanced interview (MEI) treatment aimed at parents to modify the home environment so that their children will: a) reduce """"""""screen time"""""""" or hours engaged in sedentary behaviors;b) reduce consumption of high calorie, low nutrient foods;and c) increase levels of physical activity.
These aims will be accomplished by randomizing 360 children to one of two treatment conditions: a) the En Vivo! MEI telephone and Internet based parent treatment program;and b) no-treatment control. We will examine if positive changes in selected dietary, sedentary and physical activity behaviors result in decreased weight gain and risk factors associated with type 2 diabetes. The proposed project will impact: a) body mass index (BMI), b) C-reactive protein (CRP), c) insulin resistance, d) HbA1c, as well e) behavioral and psychosocial precursors to these physical measures. Families will be randomized to the STPDPT condition or a comparison group;those in the treatment group will receive 6-9 MEI phone calls plus follow-up contact via the Internet and newsletters and comic books over a 12 month period.
Study Aims : 1) To conduct interviews with parents, teachers, and students to determine overall feasibility of MEI telephone and Internet parent diabetes prevention strategies (Fall, 2007);2) To conduct a cross sectional survey of 200 parents in the South Texas Lower Rio Grande Valley to extend and confirm findings from Aim 1 (Spring, 2008);3) To use pilot data to tailor the MEI based parent program for parents (Summer 2008);4) To assess the impact MEI based parent program on physiologic and behavioral outcomes on children aged 9-14 using randomized clinical trial methodology with 360 families (parent/child dyad) recruited from members of the Cameron County Hispanic Cohort (Fall 2008 - 2011).

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
5P20MD000170-10
Application #
8377032
Study Section
Special Emphasis Panel (ZRG1-DIG-B)
Project Start
Project End
2014-02-28
Budget Start
2012-03-01
Budget End
2013-02-28
Support Year
10
Fiscal Year
2012
Total Cost
$426,208
Indirect Cost
$113,164
Name
University of Texas Health Science Center Houston
Department
Type
DUNS #
800771594
City
Houston
State
TX
Country
United States
Zip Code
77225
Heredia, Natalia I; Lee, MinJae; Mitchell-Bennett, Lisa et al. (2017) Tu Salud ¡Sí Cuenta! Your Health Matters! A Community-wide Campaign in a Hispanic Border Community in Texas. J Nutr Educ Behav 49:801-809.e1
Wu, Shenghui; McCormick, Joseph B; Curran, Joanne E et al. (2017) Transition from pre-diabetes to diabetes and predictors of risk in Mexican-Americans. Diabetes Metab Syndr Obes 10:491-503
Gill, Clarence; Vatcheva, Kristina P; Pan, Jen-Jung et al. (2017) Frequency of Nonalcoholic Fatty Liver Disease and Subclinical Atherosclerosis Among Young Mexican Americans. Am J Cardiol 119:1717-1722
Heredia, Natalia I; Lee, MinJae; Reininger, Belinda M (2017) Exposure to a community-wide campaign is associated with physical activity and sedentary behavior among Hispanic adults on the Texas-Mexico border. BMC Public Health 17:883
Wu, Shenghui; Fisher-Hoch, Susan P; Reninger, Belinda et al. (2016) Meeting or Exceeding Physical Activity Guidelines is Associated with Reduced Risk for Cancer in Mexican-Americans. Am J Cancer Prev 4:1-7
Garza, Ariana L; Vatcheva, Kristina P; Pan, Jen-Jung et al. (2016) Liver and Other Gastrointestinal Cancers Are Frequent in Mexican Americans. J Racial Ethn Health Disparities 3:1-10
Wu, Shenghui; Fisher-Hoch, Susan P; Reninger, Belinda et al. (2016) Metabolic Health Has Greater Impact on Diabetes than Simple Overweight/Obesity in Mexican Americans. J Diabetes Res 2016:4094876
Olvera, R L; Fisher-Hoch, S P; Williamson, D E et al. (2016) Depression in Mexican Americans with diagnosed and undiagnosed diabetes. Psychol Med 46:637-46
Wu, Shenghui; Fisher-Hoch, Susan P; Reininger, Belinda et al. (2016) Recommended Levels of Physical Activity Are Associated with Reduced Risk of the Metabolic Syndrome in Mexican-Americans. PLoS One 11:e0152896
Gay, Jennifer L; Salinas, Jennifer J; Buchner, David M et al. (2015) Meeting physical activity guidelines is associated with lower allostatic load and inflammation in Mexican Americans. J Immigr Minor Health 17:574-81

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