Substantial racial/ethnic disparities exist in the area of renal health. Minority groups are more than 50% of all persons on the waiting list for a kidney transplant in the United States. Yet, because minorities donate organs at a rate that reflects their representation in the population, the shortage of kidneys for minorities with End-Stage Renal Disease has reached crisis proportions. Such trends suggest that in addition to conducting research that can better define the correlates and causes of racial/ethnic disparities in kidney transplantation rates research is also needed to identify psychosocial and psychoneuroimmunological factors that contribute to poorer health outcomes. The findings can be exported to the design of prevention campaigns and that can efficaciously reduce the prevalence of hypertension, diabetes mellitus, poor nutrition and inadequate exercise, and licit and illicit substance use among minorities. The Howard University Project Export Center of Renal Health will be structured to serve as an institutionalized and permanent research center that will complete research and test interventions and practices that can reduce current racial/ethnic differentials in renal health. The Center will be headed by Dr. Clive O. Callender, the nation's premiere kidney transplantation specialist and a pioneer in creating interventions to remedy racial/ethnic gaps in renal health.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
5P20MD000512-04
Application #
7120546
Study Section
Special Emphasis Panel (ZMD1-TLB (02))
Program Officer
Tabor, Derrick C
Project Start
2003-09-30
Project End
2010-08-31
Budget Start
2006-09-01
Budget End
2010-08-31
Support Year
4
Fiscal Year
2006
Total Cost
$1,487,771
Indirect Cost
Name
Howard University
Department
Type
Schools of Medicine
DUNS #
056282296
City
Washington
State
DC
Country
United States
Zip Code
20059
Gholson, Georica K; Mwendwa, Denée T; Wright, Regina Sims et al. (2015) The Combined Influence of Psychological Factors on Biomarkers of Renal Functioning in African Americans. Ethn Dis 25:117-22
Keen 2nd, Larry; Turner, Arlener D; Mwendwa, Denee et al. (2015) Depressive symptomatology and respiratory sinus arrhythmia in a non-clinical sample of middle-aged African Americans. Biol Psychol 108:56-61
Keen 2nd, Larry; Turner, Arlener D (2015) Differential effects of self-reported lifetime marijuana use on interleukin-1 alpha and tumor necrosis factor in African American adults. J Behav Med 38:527-34
Keen 2nd, Larry; Turner, Arlener D (2014) Association between interleukin-6 and neurocognitive performance as a function of self-reported lifetime marijuana use in a community based sample of African American adults. J Int Neuropsychol Soc 20:773-83
Keen 2nd, Larry; Pereira, Deidre; Latimer, William (2014) Self-reported lifetime marijuana use and interleukin-6 levels in middle-aged African Americans. Drug Alcohol Depend 140:156-60
Mwendwa, Denee T; Ali, Mana K; Sims, Regina C et al. (2013) Psychometric properties of the Cook Medley hostility scale and its association with inflammatory markers in African Americans. Psychol Health Med 18:431-44
Sims, Regina C; Levy, Shellie-Anne; Mwendwa, Denee T et al. (2011) The influence of functional social support on executive functioning in middle-aged African Americans. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 18:414-31
Mwendwa, Denee T; Sims, Regina C; Madhere, Serge et al. (2011) The influence of coping with perceived racism and stress on lipid levels in African Americans. J Natl Med Assoc 103:594-601
Mwendwa, Denee T; Gholson, Georica; Sims, Regina C et al. (2011) Coping with perceived racism: a significant factor in the development of obesity in African American women? J Natl Med Assoc 103:602-8
Carter, Ernest L; Nunlee-Bland, Gail; Callender, Clive (2011) A patient-centric, provider-assisted diabetes telehealth self-management intervention for urban minorities. Perspect Health Inf Manag 8:1b

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