4.2.2. Thematic Focus The overall theme of the Research Core is to stimulate and advance multi-level, interdisciplinary and community-engaged health services research to reduce health disparities that adversely affect vulnerable, racial and ethnic minorities. A major focus of our Center will be to investigate the diffusion of health interventions that have been found to be enormously beneficial to society in general, but whose impact on minority populations is less clear. What we are proposing is that many beneficial biological interventions may have unintended adverse effects within minority populations, or at the very least, may not yield results equitable to those found among whites. The two studies included in this Center application examine two different aspects of the diffusion of health innovations in minority populations. Our overarching hypothesis is that the independent and interrelated effects of individual, community, and systems-level factors provide both the context and determinants for health disparities between whites and racial and ethnic minorities. It assumes that disparities in health build upon vulnerabilities caused by social and economic inequalities and characteristics which affect the speed of diffusion of health innovations to different segments of our society. The sum of proposed Center activities is not only to advance scientific understanding of the relationship between individual, community, and macro social factors, including the effects of public policies and health, but to identify and disseminate knowledge about key pathways for reducing disparities to clinical and community partners. The primary goals of the Research Core are to: a) develop a strong, inter-disciplinary, core group of researchers, steeped in a systems framework, knowledgeable about a multi-level approach, and trained in health services research methods;b) assist project investigators focus their research on culturally relevant interventions to improve the health of underserved populations and to pave the way for the elimination of health disparities;c) provide opportunities for investigators to use secondary data sets to test relevant hypotheses and generate new knowledge;and d) successfully submit articles for publication and compete for investigator initiated research grants.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Exploratory Grants (P20)
Project #
Application #
Study Section
Special Emphasis Panel (ZRG1-EMNR-B)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Meharry Medical College
United States
Zip Code
Hagan, Ronald D; Langston, Michael A; Wang, Kai (2016) Lower Bounds on Paraclique Density. Discrete Appl Math 204:208-212
Selove, Rebecca; Kilbourne, Barbara; Fadden, Mary Kay et al. (2016) Time from Screening Mammography to Biopsy and from Biopsy to Breast Cancer Treatment among Black and White, Women Medicare Beneficiaries Not Participating in a Health Maintenance Organization. Womens Health Issues 26:642-647
Clark, Ryan S; Pellom, Samuel T; Booker, Burthia et al. (2016) Validation of research trajectory 1 of an Exposome framework: Exposure to benzo(a)pyrene confers enhanced susceptibility to bacterial infection. Environ Res 146:173-84
Rust, George; Zhang, Shun; Malhotra, Khusdeep et al. (2015) Paths to health equity: Local area variation in progress toward eliminating breast cancer mortality disparities, 1990-2009. Cancer 121:2765-74
Sanderson, Maureen; Levine, Robert S; Fadden, Mary K et al. (2015) Mammography Screening Among the Elderly: A Research Challenge. Am J Med 128:1362.e7-14
Wang, Kai; Phillips, Charles A; Saxton, Arnold M et al. (2015) EntropyExplorer: an R package for computing and comparing differential Shannon entropy, differential coefficient of variation and differential expression. BMC Res Notes 8:832
Schoenrock, Andrew; Samanfar, Bahram; Pitre, Sylvain et al. (2014) Efficient prediction of human protein-protein interactions at a global scale. BMC Bioinformatics 15:383
Teich, Alice S; Barnett, Josephine; Bonuck, Karen (2014) Women's perceptions of breastfeeding barriers in early postpartum period: a qualitative analysis nested in two randomized controlled trials. Breastfeed Med 9:9-15
Juarez, Paul D; Matthews-Juarez, Patricia; Hood, Darryl B et al. (2014) The public health exposome: a population-based, exposure science approach to health disparities research. Int J Environ Res Public Health 11:12866-95
Hull, Pamela C; Reece, Michelle C; Patton, Marian et al. (2014) A community-based oral health self-care intervention for Hispanic families. Int J Public Health 59:61-6

Showing the most recent 10 out of 60 publications