: The University of Texas at Brownsville and Texas Southmost College (UTB/TSC) is a Hispanic-serving institution that resides in the southernmost tip of Texas with a predominantly Hispanic, poor, and underserved population. The university has made remarkable progress over the last ten years towards developing competitive research programs. UTB/TSC seeks to continue the university's momentum in research infrastructure development. UTB/TSC has prioritized biomedical research for the investigation of diseases that affect this population and is positioned to become the leading health related research institution that addresses health disparities and the growing health needs of the region. The continuation of the RIMI program will provide the mechanism for UTB/TSC to accelerate the implementation of the university's research plans through enhancing research facilities and the research environment for students and faculty. The five-year plan emphasizes four core functions to create an active and supportive research environment for faculty and future scientists. These cores include 1) strengthening the research infrastructure that sustains and enhances biomedical research at UTB/TSC;2) enhancing the research training capacity to further develop junior research scientists through career development planning;3) developing curricular changes and student training activities that will improve student preparation in biomedical science research and health professions, and 4) enhancing the imaging research facilities through the acquisition of advanced instrumentation. The RIMI project will develop a cadre of biomedical and clinical research scientists with the skills and knowledge to engage in leading edge research that contributes to the reduction of health disparities. The development of sustainable biomedical research at UTB/TSC will create knowledge, impact developing junior faculty and students, generate significant resources for the development of research at our minority institution, and contribute to eliminating health disparities in the United States.

Public Health Relevance

This project will enhance the research infrastructure and capacity building at this minority-serving institution; create training and career development opportunities to nurture new investigators;improve the curriculum and build the academic programs to better prepare student (majority Hispanic) to be involved in health and health disparity research within the strategic plans of Health People 2010 and mission of NIH.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Exploratory Grants (P20)
Project #
Application #
Study Section
Special Emphasis Panel (ZMD1-PA (R3))
Program Officer
Mcclure, Shelia A
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University/Texas Brownsville & Southmost Coll
Other Domestic Higher Education
United States
Zip Code
Unterweger, Daniel; Miyata, Sarah T; Bachmann, Verena et al. (2014) The Vibrio cholerae type VI secretion system employs diverse effector modules for intraspecific competition. Nat Commun 5:3549
Cox, N; Toro, B; Pacheco-Otalora, L F et al. (2014) An endoplasmic reticulum trafficking signal regulates surface expression of ?4 subunit of a voltage- and Ca²?-activated K? channel. Brain Res 1553:12-23
Gonzales, Miguel F; Brooks, Teresa; Pukatzki, Stefan U et al. (2013) Rapid protocol for preparation of electrocompetent Escherichia coli and Vibrio cholerae. J Vis Exp :
Ermolinsky, Boris; Peredelchuk, Michael; Provenzano, Daniele (2013) ?-Cyclodextrin decreases cholera toxin binding to GM1-gangliosides. J Med Microbiol 62:1011-4
Upreti, Chirag; Otero, Rafael; Partida, Carlos et al. (2012) Altered neurotransmitter release, vesicle recycling and presynaptic structure in the pilocarpine model of temporal lobe epilepsy. Brain 135:869-85
Wein, Alexander N; Williams, Brian N; Liu, Shihui et al. (2012) Small molecule inhibitors of Bacillus anthracis protective antigen proteolytic activation and oligomerization. J Med Chem 55:7998-8006
Unterweger, Daniel; Kitaoka, Maya; Miyata, Sarah T et al. (2012) Constitutive type VI secretion system expression gives Vibrio cholerae intra- and interspecific competitive advantages. PLoS One 7:e48320
Garrido-Sanabria, Emilio R; Perez-Cordova, Miriam G; Colom, Luis V (2011) Differential expression of voltage-gated K+ currents in medial septum/diagonal band complex neurons exhibiting distinct firing phenotypes. Neurosci Res 70:361-9
Oliveira, Mauro Schneider; Pacheco, Luis Fernando; Mello, Carlos Fernando et al. (2011) Epileptiform activity in the limbic system. Front Biosci (Schol Ed) 3:565-93
Ermolinsky, Boris S; Skinner, Frank; Garcia, Ileana et al. (2011) Upregulation of STREX splice variant of the large conductance Ca2+-activated potassium (BK) channel in a rat model of mesial temporal lobe epilepsy. Neurosci Res 69:73-80

Showing the most recent 10 out of 24 publications