The advent of anti-retroviral nnedications, introduction of highly active anti-retroviral therapy (HAART), and advances in treatment options have transformed HIV disease from an acute terminal disease to a chronic manageable disease. These life-extending treatments can reduce the morbidity and mortality associated with the disease among persons living with HIV/AIDS (PLWHA). Engagement in care is vital for HIV treatment success at both the individual and population levels.^ Although financial barriers to seeking HIV care have been reduced through mechanisms such as the Ryan White Act, a large subset of PLWHA does not remain in 1 2 care. ? Identifying personal, organizational, and environmental factors that influence patterns of utilization of HIV care among PLWHA is critical to developing strategies to increase initiation of care among them, those who are not in care and retention, and those who have episodic patterns of care utilization. The goal of the HIV care research project is to work with a local community to identify and document psychosocial, cultural, and structural barriers that deter PLWHA in a rural, majority African-American, southern South Carolina (SC) county from initiating and continuing HIV care. Findings of this study will inform development of a pilot, community-initiated intervention to improve initiation and continuation of HIV care among PLWHA.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
7P20MD001770-09
Application #
8580138
Study Section
Special Emphasis Panel (ZMD1-PA)
Project Start
2013-03-04
Project End
2015-02-28
Budget Start
2013-03-01
Budget End
2014-02-28
Support Year
9
Fiscal Year
2013
Total Cost
$100,747
Indirect Cost
$26,646
Name
University of South Carolina at Columbia
Department
Type
DUNS #
041387846
City
Columbia
State
SC
Country
United States
Zip Code
29208
Xu, Hanwen; Zhang, Yu; Altomare, Diego et al. (2014) Six1 promotes epithelial-mesenchymal transition and malignant conversion in human papillomavirus type 16-immortalized human keratinocytes. Carcinogenesis 35:1379-88
Rice, LaShanta J; Jiang, Chengsheng; Wilson, Sacoby M et al. (2014) Use of segregation indices, Townsend Index, and air toxics data to assess lifetime cancer risk disparities in metropolitan Charleston, South Carolina, USA. Int J Environ Res Public Health 11:5510-26
Jaggers, Jason R; Dudgeon, Wesley D; Burgess, Stephanie et al. (2014) Psychological correlates of HIV-related symptom distress. J Assoc Nurses AIDS Care 25:309-17
Kowli, Sangeeta; Velidandla, Rupa; Creek, Kim E et al. (2013) TGF-? regulation of gene expression at early and late stages of HPV16-mediated transformation of human keratinocytes. Virology 447:63-73
Altomare, Diego; Velidandla, Rupa; Pirisi, Lucia et al. (2013) Partial loss of Smad signaling during in vitro progression of HPV16-immortalized human keratinocytes. BMC Cancer 13:424
Chen, Yi; Pirisi, Lucia; Creek, Kim E (2013) Ski protein levels increase during in vitro progression of HPV16-immortalized human keratinocytes and in cervical cancer. Virology 444:100-8
Bellinger, Jessica D; Hassan, Rahnuma M; Rivers, Patrick A et al. (2010) Specialty care use in US patients with chronic diseases. Int J Environ Res Public Health 7:975-90
Glover, Saundra; Rivers, Patrick A; Asoh, Derek A et al. (2010) Data mining for health executive decision support: an imperative with a daunting future! Health Serv Manage Res 23:42-6
Davis, Jennifer R; Wilson, Sacoby; Brock-Martin, Amy et al. (2010) The impact of disasters on populations with health and health care disparities. Disaster Med Public Health Prep 4:30-8
Dudgeon, Wesley David; Phillips, Kenneth Doyle; Durstine, John Larry et al. (2010) Individual exercise sessions alter circulating hormones and cytokines in HIV-infected men. Appl Physiol Nutr Metab 35:560-8

Showing the most recent 10 out of 26 publications