The Center for Allaying Health Disparities through Research and Education (CADRE) Project is a multidisciplinary effort to build a Central State University (CSU) research capacity that will ultimately contribute to the elimination of disparities between the health of the minority and majority populations in the United States. CSU, a public Historically Black College/University (HBCU) in Ohio will address the issue by increasing our capacity to conduct bio medical research through the following: 1) Developing a Biotechnology Laboratory;2) Developing a Human Exercise and Performance Laboratory;3) Building a first class animal facility;4) Developing a Geospatial Database Center for Minority Health Disparities;and 4) Developing a Psychology Testing Laboratory. We will also conduct three independent research projects namely: 1) Cell &Extra cellular Matrix Interactions in Development of Tissue Engineered Cartilage;2) Isolation and Characterization of Snake Venom Toxins to Combat Prostate Cancer in African-Americans;and 3) Closing the Health Disparity Gap: Impact of Health Empowerment Technologies on Elderly African American Health Provider Relationships. As an HBCU, CSU graduates have personal knowledge and experience of the disparities in health care.
Specific Aims of the CADRE Project are: # of faculty conducting research;# of presentations made at-national meetings;Increase in research funding;# of publications hi peer reviewed journals;# of graduates from departments;# of students to enter graduate, professional or medical school;and # of research courses (# of students taking classes). Therefore, a critical goal of this project is to increase the number of CSU graduates who enter graduate and professional schools in health related fields that will have an impact in the minority health arena. As a part of our capacity building plan, we will collaborate with the University of Cincinnati to improve our administrative abilities in order to better manage our anticipated increased research efforts. Finally, we intend on increasing the capacity of the entire university faculty to solicit external funds by training and encouraging them to write proposals and to enhance the credentials of the faculty, and the university, by encouraging them to publish articles in peer reviewed journals.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Exploratory Grants (P20)
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Special Emphasis Panel (ZMD1-LW (10))
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Hunter, Deloris
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Central State University (Wilberforce, OH)
Other Domestic Higher Education
United States
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Kim, Wangdo; Espanha, Margarida M; Veloso, António P et al. (2013) An Informational Algorithm as the Basis for Perception-Action Control of the Instantaneous Axes of the Knee. J Nov Physiother 3:127
Kim, Wangdo; Kim, Yoon-Hyuk; Veloso, Antonio P et al. (2013) Tracking Knee Joint Functional Axes through Tikhonov Filtering and Plucker Coordinates. J Nov Physiother Suppl 4:
Winbush, Greta Berry; McDougle, Leon; Labranche, Lynda et al. (2013) Health empowerment technologies (HET): building a web-based tool to empower older African American patient-doctor relationships. J Health Care Poor Underserved 24:106-17
Kohles, Sean S; Mason, Shelley S; Adams, Anya P et al. (2012) Ultrasonic wave propagation assessment of native cartilage explants and hydrogel scaffolds for tissue engineering. Int J Biomed Eng Technol 10:296-307
Saha, Asit K; Kohles, Sean S (2012) A cell-matrix model of anabolic and catabolic dynamics during cartilage biomolecule regulation. Int J Comput Healthc 1:214-228
Kim, Wangdo; Kohles, Sean S (2012) A reciprocal connection factor for assessing knee-joint function. Comput Methods Biomech Biomed Engin 15:911-7
Saha, Asit K; Liang, Yu; Kohles, Sean S (2011) Biokinetic Mechanisms Linked With Musculoskeletal Health Disparities: Stochastic Models Applying Tikhonov's Theorem to Biomolecule Homeostasis. J Nanotechnol Eng Med 2:21004-21012
Mason, Shelley S; Kohles, Sean S; Zelick, Randy D et al. (2011) Three-Dimensional Culture of Cells and Matrix Biomolecules for Engineered Tissue Development and Biokinetics Model Validation. J Nanotechnol Eng Med 2:25001-25007
Kohles, Sean S; Liang, Yu; Saha, Asit K (2011) Volumetric stress-strain analysis of optohydrodynamically suspended biological cells. J Biomech Eng 133:011004
Saha, Asit K; Kohles, Sean S (2010) A Distinct Catabolic to Anabolic Threshold Due to Single-Cell Static Nanomechanical Stimulation in a Cartilage Biokinetics Model. J Nanotechnol Eng Med 1:

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