The Center for Allaying Health Disparities through Research and Education (CADRE) Project is a multidisciplinary effort to build a Central State University (CSU) research capacity that will ultimately contribute to the elimination of disparities between the health of the minority and majority populations in the United States. CSU, a public Historically Black College/University (HBCU) in Ohio will address the issue by increasing our capacity to conduct bio medical research through the following: 1) Developing a Biotechnology Laboratory;2) Developing a Human Exercise and Performance Laboratory;3) Building a first class animal facility;4) Developing a Geospatial Database Center for Minority Health Disparities;and 4) Developing a Psychology Testing Laboratory. We will also conduct three independent research projects namely: 1) Cell &Extra cellular Matrix Interactions in Development of Tissue Engineered Cartilage;2) Isolation and Characterization of Snake Venom Toxins to Combat Prostate Cancer in African-Americans;and 3) Closing the Health Disparity Gap: Impact of Health Empowerment Technologies on Elderly African American Health Provider Relationships. As an HBCU, CSU graduates have personal knowledge and experience of the disparities in health care.
Specific Aims of the CADRE Project are: # of faculty conducting research;# of presentations made at-national meetings;Increase in research funding;# of publications hi peer reviewed journals;# of graduates from departments;# of students to enter graduate, professional or medical school;and # of research courses (# of students taking classes). Therefore, a critical goal of this project is to increase the number of CSU graduates who enter graduate and professional schools in health related fields that will have an impact in the minority health arena. As a part of our capacity building plan, we will collaborate with the University of Cincinnati to improve our administrative abilities in order to better manage our anticipated increased research efforts. Finally, we intend on increasing the capacity of the entire university faculty to solicit external funds by training and encouraging them to write proposals and to enhance the credentials of the faculty, and the university, by encouraging them to publish articles in peer reviewed journals.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
5P20MD003350-05
Application #
8294455
Study Section
Special Emphasis Panel (ZMD1-LW (10))
Program Officer
Hunter, Deloris
Project Start
2008-09-30
Project End
2014-06-30
Budget Start
2012-07-16
Budget End
2014-06-30
Support Year
5
Fiscal Year
2012
Total Cost
$848,302
Indirect Cost
$255,351
Name
Central State University (Wilberforce, OH)
Department
None
Type
Other Domestic Higher Education
DUNS #
008873747
City
Wilberforce
State
OH
Country
United States
Zip Code
45384
Kim, Wangdo; Kim, Yoon-Hyuk; Veloso, Antonio P et al. (2013) Tracking Knee Joint Functional Axes through Tikhonov Filtering and Plucker Coordinates. J Nov Physiother Suppl 4:
Winbush, Greta Berry; McDougle, Leon; Labranche, Lynda et al. (2013) Health empowerment technologies (HET): building a web-based tool to empower older African American patient-doctor relationships. J Health Care Poor Underserved 24:106-17
Saha, Asit K; Liang, Yu; Kohles, Sean S (2011) Biokinetic Mechanisms Linked With Musculoskeletal Health Disparities: Stochastic Models Applying Tikhonov's Theorem to Biomolecule Homeostasis. J Nanotechnol Eng Med 2:21004-21012
Mason, Shelley S; Kohles, Sean S; Zelick, Randy D et al. (2011) Three-Dimensional Culture of Cells and Matrix Biomolecules for Engineered Tissue Development and Biokinetics Model Validation. J Nanotechnol Eng Med 2:25001-25007
Kohles, Sean S; Liang, Yu; Saha, Asit K (2011) Volumetric stress-strain analysis of optohydrodynamically suspended biological cells. J Biomech Eng 133:011004
Saha, Asit K; Kohles, Sean S (2010) Periodic Nanomechanical Stimulation in a Biokinetics Model Identifying Anabolic and Catabolic Pathways Associated With Cartilage Matrix Homeostasis. J Nanotechnol Eng Med 1:
Wilson, Zachary D; Kohles, Sean S (2010) Two-Dimensional Modeling of Nanomechanical Strains in Healthy and Diseased Single-Cells During Microfluidic Stress Applications. J Nanotechnol Eng Med 1:21005
Saha, Asit K; Kohles, Sean S (2010) A Distinct Catabolic to Anabolic Threshold Due to Single-Cell Static Nanomechanical Stimulation in a Cartilage Biokinetics Model. J Nanotechnol Eng Med 1:
Kim, Wangdo; Kohles, Sean S (2009) Optical acquisition and polar decomposition of the full-field deformation gradient tensor within a fracture callus. J Biomech 42:2026-32
Kohles, Sean S; Neve, Nathalie; Zimmerman, Jeremiah D et al. (2009) Mechanical stress analysis of microfluidic environments designed for isolated biological cell investigations. J Biomech Eng 131:121006

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