The mission of the DILLARD-LSUHSC Minority Health and Health Disparities Research Center (MHHDRC) is to improve the health of underserved populations in New Orleans and surrounding regions, through the combined strengths of two institutions that have traditionally served minority populations. The Center will address a widespread and persistent problem: Low participation in clinical trials furthers health disparities. Dillard University, a historically black college, has an international reputation for preparing minorities for careers in health sciences. Through its nine public hospitals, clinics, and Minority-Based Community Clinical Oncology Program, the LSU Health Sciences Center (LSUHSC) provides healthcare for more minorities than any other facility in the state. The MHHDRC will address two problems: 1) a disproportionate number of minorities pursuing health disparities research, and 2) a shortage of minority clinical research associates (CRAs) to promote and conduct clinical trials within health disparity communities. The Center's goals are to conduct health disparities research, develop minority faculty to become successful investigators, expose undergraduates to health disparity research, and train minority CRAs. The overarching goal is to develop evidenced-based methodologies for increasing minority participation in clinical trials. These will have particular relevance in light of the region's disproportionate share of health disparities, a situation that was aggravated by Hurricane Katrina. The Center will rebuild and create new infrastructure at Dillard, where it will be located. Goals will be realized through integrated research, training, and community engagement. These will be incorporated into clinical and translational research projects that focus on chronic conditions accounting for a disproportionate share of disease among health disparity populations. The research component will pair new investigators with established ones. Training will focus on educating undergraduate students in health disparities research and outreach and on training nurses to conduct clinical trials and promote the inclusion of underrepresented minorities. Community engagement will reduce health disparities by increasing the participation of minority and underserved populations.

Public Health Relevance

The lack of well trained biomedical investigators and research nurses decreases minority participation in clinical and basic research, denying them access to advanced healthcare and perpetuating health disparities. The proposed Center will promote the participation of minority investigators, nurses, undergraduate students, and communities in health-related research that affects their community.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
5P20MD004817-04
Application #
8434763
Study Section
Special Emphasis Panel (ZMD1-PA (03))
Program Officer
Tabor, Derrick C
Project Start
2010-05-16
Project End
2015-02-28
Budget Start
2013-03-05
Budget End
2014-02-28
Support Year
4
Fiscal Year
2013
Total Cost
$1,172,802
Indirect Cost
$130,347
Name
Dillard University
Department
Other Health Professions
Type
Schools of Nursing
DUNS #
062665468
City
New Orleans
State
LA
Country
United States
Zip Code
70122
Koochekpour, Shahriar; Buckles, Erick; Shourideh, Mojgan et al. (2014) Androgen receptor mutations and polymorphisms in African American prostate cancer. Int J Biol Sci 10:643-51
Zabaleta, J; Velasco-Gonzalez, C; Estrada, J et al. (2014) Inverse correlation of serum inflammatory markers with metabolic parameters in healthy, Black and White prepubertal youth. Int J Obes (Lond) 38:563-8
Liu, Zun; Rebowe, Ryan E; Wang, Zemin et al. (2014) KIF3a promotes proliferation and invasion via Wnt signaling in advanced prostate cancer. Mol Cancer Res 12:491-503
Hurst, Charlotte; Dennis, Betty P (2013) Developing a clinical research associate training program at Dillard University: the impact of collaboration. ABNF J 24:104-10
Koochekpour, Shahriar; Hu, Siyi; Vellasco-Gonzalez, Cruz et al. (2012) Serum prosaposin levels are increased in patients with advanced prostate cancer. Prostate 72:253-69
Koochekpour, Shahriar (2010) Androgen receptor signaling and mutations in prostate cancer. Asian J Androl 12:639-57