Center of Excellence for Cancer Research, Community Engagement/Outreach Core (CEOC)- Dr. Saleh M. M. Rahman. The mission of the CEOC is to develop, enhance, and strengthen partnerships with the Gadsden and Leon County African American communities to create a sustainable research and outreach environment for eliminating breast cancer disparities. The community engagement/outreach core has envisioned the following Aims: (1) Build capacity of academic and community partners to conduct Community Based Participatory Research (CBPR) to reduce breast cancer disparities;(2) Develop, implement and evaluate theory-driven, culturally sensitive outreach activities to improve health literacy, breast cancer screening and awareness of breast cancer disparity;and (3) Provide culturally appropriate outreach services to community members, support local outreach efforts and disseminate breast cancer and health information. This mission will be accomplished by the following processes: 1) Implementing participatory research methods to engage community in sustainable breast cancer research: Using this approach, we have established partnerships with 5 community-based organizations in Gadsden and Leon Counties from the beginning of this project and we propose a series of media campaign methods, such as convening of informational meetings, mobile video shows, brochures, advertisements and information booklets targeting community and academic stakeholders. As part of our participatory approach, we already have included a key community liaison and identified three community advisors and other stakeholder who have participated actively in prioritizing the center activities, intervention and service components of the CEOC. 2) Develop, implement and evaluate theory-driven, culturally sensitive outreach activities to improve health literacy, breast cancer screening and awareness of breast cancer disparities. A combination of community, behavioral and communication theories will be used to develop culturally appropriate outreach activities. To address the issue of cultural appropriateness the center will implement a faith-based outreach and education component called """"""""The Bible Bookmark"""""""" and Faith-Based Resource Tool Kit. To increase participation in the process the center will implement periodic health revival in the community;to increase knowledge and awareness and to increase health literacy about breast cancer, cancer disparity, prevention and healthy life-style, the center will create a video-based mobile education campaign, brochures and information booklets. These materials will be assessed for readability and cultural sensitivity using the Flesch Reading Ease, Flesch-Kincaid, and Cultural Sensitivity Assessment Tools. The CEOC will also focus on psychological health of the participants and a patient referral service will be established with Tallahassee Memorial Hospital Cancer Center. 3) Provide culturally appropriate outreach services to community members, support local outreach efforts and disseminate cancer and health information by creating a cadre of women to remind each other for screening (Project TREE). The CEOC will be evaluated, at process, impact and outcome levels with cleariy defined indicators: partnership development, trust, community engagement level, reciprocity, knowledge and behavioral intention change, health literacy change, changes in psychological health outcomes, BC screening rates, BC survival rates, participants'satisfaction and changes in overall disparities. All measures will be done using related standardized measurement tools.

Public Health Relevance

To reduce health disparities, the importance of community engagement and outreach cannot be overemphasized. CBPR has emerged as alternative research paradigm which integrates education and social action by engaging and empowering communities to improve health and reduce health disparities. The proposed CEOC is conceptualized based evidence-based practices in community health which has high relevance in public health, cancer disparities in particular.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
5P20MD006738-03
Application #
8611742
Study Section
Special Emphasis Panel (ZMD1-RN)
Project Start
Project End
Budget Start
2014-02-01
Budget End
2015-01-31
Support Year
3
Fiscal Year
2014
Total Cost
$145,021
Indirect Cost
$38,279
Name
Florida Agricultural and Mechanical University
Department
Type
DUNS #
623751831
City
Tallahassee
State
FL
Country
United States
Zip Code
32307
Godugu, Chandraiah; Doddapaneni, Ravi; Singh, Mandip (2017) Honokiol nanomicellar formulation produced increased oral bioavailability and anticancer effects in triple negative breast cancer (TNBC). Colloids Surf B Biointerfaces 153:208-219
Mack, Nzinga; Mazzio, Elizabeth A; Bauer, David et al. (2017) Stable shRNA Silencing of Lactate Dehydrogenase A (LDHA) in Human MDA-MB-231 Breast Cancer Cells Fails to Alter Lactic Acid Production, Glycolytic Activity, ATP or Survival. Anticancer Res 37:1205-1212
Doddapaneni, Ravi; Patel, Ketan; Chowdhury, Nusrat et al. (2017) Reversal of drug-resistance by noscapine chemo-sensitization in docetaxel resistant triple negative breast cancer. Sci Rep 7:15824
Messeha, Samia S; Zarmouh, Najla O; Mendonca, Patricia et al. (2017) The attenuating effects of plumbagin on pro-inflammatory cytokine expression in LPS-activated BV-2 microglial cells. J Neuroimmunol 313:129-137
Mazzio, Elizabeth A; Bauer, David; Mendonca, Patricia et al. (2017) Natural product HTP screening for attenuation of cytokine-induced neutrophil chemo attractants (CINCs) and NO2- in LPS/IFN? activated glioma cells. J Neuroimmunol 302:10-19
Kutlehria, Shallu; Behl, Gautam; Patel, Ketan et al. (2017) Cholecalciferol-PEG Conjugate Based Nanomicelles of Doxorubicin for Treatment of Triple-Negative Breast Cancer. AAPS PharmSciTech :
Mazzio, Elizabeth A; Soliman, Karam F A (2017) HTP Nutraceutical Screening for Histone Deacetylase Inhibitors and Effects of HDACis on Tumor-suppressing miRNAs by Trichostatin A and Grapeseed (Vitis vinifera) in HeLa cells. Cancer Genomics Proteomics 14:17-33
Mendonca, Patricia; Taka, Equar; Bauer, David et al. (2017) The attenuating effects of 1,2,3,4,6 penta-O-galloyl-?-d-glucose on inflammatory cytokines release from activated BV-2 microglial cells. J Neuroimmunol 305:9-15
Ali, Askal Ayalew; Xiao, Hong; Tawk, Rima et al. (2017) Comparison of health utility weights among elderly patients receiving breast-conserving surgery plus hormonal therapy with or without radiotherapy. Curr Med Res Opin 33:391-400
Mathis, Arlesia L; Rooks, Ronica N; Tawk, Rima H et al. (2017) Neighborhood Influences and BMI in Urban Older Adults. J Appl Gerontol 36:692-708

Showing the most recent 10 out of 93 publications