The major responsibilities ofthe administrative core will be to manage day-to-day personnel and fiscal matters of the Texas Center for Health Disparities, promote collaboration among cores and projects, facilitate translation of science into practice and engage community partners in activities that can lead to successful intervention strategies to eliminate women's health disparities. Specific duties include oversight and management ofthe budget, ensuring project compliance, providing logistical support for all inter-campus and campus-agency activities, implementation ofthe project's evaluation plan and preparation of all required reports. Activities of this core will include scheduling meetings and organizing workshops for investigators and consultants, including external advisors and collaborators. A major objective will be to facilitate communication between the research, education/training and outreach cores such that the programs and projects become interactive and synergize with one another. Another objective of the administrative core during the award period is to maintain a vibrant website that will be used by our community partners, researchers and general public. It is anticipated that the TCHD would become recognized as a focal point from which all regional and state activities relating to minority health could be readily accessed. The administrative core will also serve as the planning/evaluation core shared between URM and community partners and function to evaluate and prioritize new project proposals, recruit new associates and investigators and establish infrastructure resources on the basis of their consonance with the center's goals and objectives. The direct administrative oversight ofthe Center will be performed by the Program Executive Committee. The Program Executive committee will rely on input from the External Advisory Board, Translational Research Advisory Board, Community Advisory Board and the Internal Advisory Committee to ensure that the Center activities conform to the strategic plans of the NIMHD and UNTHSC. The expected outcome will be enabling research aimed at eliminating health disparities, mentoring minority students and faculty to become health professionals and reaching out to the minority communities to facilitate understanding and elimination of health disparities.
Despite the overall improvement in the health of Americans dunng the past two decades, significant disparities in health outcomes persist based on race and ethnicity, sex, level of education and income, and other social characteristics. Through an integrated approach, the administrative core of TCHD will help in combating the disparities in women's health such as cancer, obesity and HIV.
|Griner, Nicholas B; Young, Denise; Chaudhary, Pankaj et al. (2015) ERG oncoprotein inhibits ANXA2 expression and function in prostate cancer. Mol Cancer Res 13:368-79|
|Rajendiran, Smrithi; Parwani, Anil V; Hare, Richard J et al. (2014) MicroRNA-940 suppresses prostate cancer migration and invasion by regulating MIEN1. Mol Cancer 13:250|
|Valapala, Mallika; Maji, Sayantan; Borejdo, Julian et al. (2014) Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis. J Biol Chem 289:15915-26|
|Chaudhary, Pankaj; Vishwanatha, Jamboor K (2014) c-Jun NH2-terminal kinase-induced proteasomal degradation of c-FLIPL/S and Bcl2 sensitize prostate cancer cells to Fas- and mitochondria-mediated apoptosis by tetrandrine. Biochem Pharmacol 91:457-73|
|Chaudhary, Pankaj; Sharma, Rajendra; Sahu, Mukesh et al. (2013) 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway. J Biol Chem 288:20532-46|