Abstract

Public Health Relevance

Reducing age and race-related health disparities in HIV research, and discovering brain biomarkers for early identification of persons at risk for adverse cognitive and motor outcomes in HIV, are high public health priorities. This study addresses both priorities by examining the combined effects of age and race on inflammation-related brain abnormalities in HIV, and associations with cognitive and motor function

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Exploratory Grants (P20)
Project #
1P20MD006886-01
Application #
8356061
Study Section
Special Emphasis Panel (ZMD1-RN (01))
Project Start
2012-05-25
Project End
2017-01-31
Budget Start
2012-05-25
Budget End
2013-01-31
Support Year
1
Fiscal Year
2012
Total Cost
$181,021
Indirect Cost
$51,638

  Institution

Name
Rush University Medical Center
Department
Type
DUNS #
068610245
City
Chicago
State
IL
Country
United States
Zip Code
60612

  Publications

Rodrigues, Jovita; Capuano, Ana W; Barnes, Lisa L et al. (2018) Effect of Antidepressant Medication Use and Social Engagement on the Level of Depressive Symptoms in Community-Dwelling, Older African Americans and Whites With Dementia. J Aging Health :898264318772983
Jansen, Willemijn J; Wilson, Robert S; Visser, Pieter Jelle et al. (2018) Age and the association of dementia-related pathology with trajectories of cognitive decline. Neurobiol Aging 61:138-145
Nguyen, Annie L; McNeil, Candice J; Han, S Duke et al. (2018) Risk and protective factors for health-related quality of life among persons aging with HIV. AIDS Care 30:518-522
Krueger, Kristin R; Adeyemi, Oluwatoyin; Leurgans, Sue et al. (2017) Association of cognitive activity and neurocognitive function in blacks and whites with HIV. AIDS 31:437-441
Han, S Duke; Adeyemi, Oluwatoyin; Wilson, Robert S et al. (2017) Loneliness in Older Black Adults with Human Immunodeficiency Virus Is Associated with Poorer Cognition. Gerontology 63:253-262
Turner, Arlener D; James, Bryan D; Capuano, Ana W et al. (2017) Perceived Stress and Cognitive Decline in Different Cognitive Domains in a Cohort of Older African Americans. Am J Geriatr Psychiatry 25:25-34
Arvanitakis, Zoe; Fleischman, Debra A; Arfanakis, Konstantinos et al. (2016) Association of white matter hyperintensities and gray matter volume with cognition in older individuals without cognitive impairment. Brain Struct Funct 221:2135-46
Lim, Andrew S P; Fleischman, Debra A; Dawe, Robert J et al. (2016) Regional Neocortical Gray Matter Structure and Sleep Fragmentation in Older Adults. Sleep 39:227-35
Arfanakis, Konstantinos; Wilson, Robert S; Barth, Christopher M et al. (2016) Cognitive activity, cognitive function, and brain diffusion characteristics in old age. Brain Imaging Behav 10:455-63
Fleischman, Debra A; Yang, Jingyun; Arfanakis, Konstantinos et al. (2015) Physical activity, motor function, and white matter hyperintensity burden in healthy older adults. Neurology 84:1294-300

Showing the most recent 10 out of 21 publications