Symptoms, subjective perceptions of alterations in normal bodily function and sensation or cognition, can precipitate severe psychological and physical distress and adversely affect quality of life. These detrimental effects have led to ethical imperatives to build a strong scientific basis for symptom assessment and management at all phases of the health-illness trajectory. Previous symptom research has primarily focused on the frequency and severity of a single symptom within the context of a specific illness. However, recent evidence suggests that symptoms are complex, multidimensional phenomena and that studying relationships among symptoms and symptom interactions is also critical to developing evidenced-based, cost-effective interventions. Some researchers have documented significant relationships between a variety of symptoms while others have found that the experience of symptom clusters has a significant impact on illness appraisal, coping, self-efficacy, and function status. Thus, there is a compelling body of scientific literature suggesting that addressing symptom relationships and interactions may lead to a more comprehensive approach to symptom management. Therefore, the purpose of this continuation application is to refine and expand the Center for Research on Symptoms, Symptom Interactions, and Health Outcomes within the Nell Hodgson Woodruff School of Nursing at Emory University. The goal of the Center is to facilitate the examination of symptoms and related health outcomes at this increased level of complexity using novel theoretical perspectives and more complex methodological approaches.
The specific aims are: I. Increase scholarly contributions to the scientific basis for symptom assessment and management. II. Expand the infrastructure supporting studies of symptoms, symptom interactions, and health outcomes. Ill . Augment interdisciplinary linkages and collaborative research to enhance and facilitate the study through systematic investigation of symptoms, symptom interactions, and health outcomes. And facilitate the establishment of related programs of research of symptoms, symptom interactions, and health outcomes through shared clinical, theoretical, and methodological perspectives and resources. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Exploratory Grants (P20)
Project #
5P20NR007798-06
Application #
7254948
Study Section
Special Emphasis Panel (ZNR1-REV-A (60))
Program Officer
Jett, Kathleen
Project Start
2001-07-01
Project End
2009-06-30
Budget Start
2007-09-06
Budget End
2009-06-30
Support Year
6
Fiscal Year
2007
Total Cost
$302,168
Indirect Cost
Name
Emory University
Department
Other Health Professions
Type
Schools of Nursing
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Butts, Brittany; Higgins, Melinda; Dunbar, Sandra et al. (2018) The Third Time's a Charm: Psychometric Testing and Update of the Atlanta Heart Failure Knowledge Test. J Cardiovasc Nurs 33:13-21
Reilly, Carolyn Miller; Higgins, Melinda; Smith, Andrew et al. (2015) Single subject design: Use of time series analyses in a small cohort to understand adherence with a prescribed fluid restriction. Appl Nurs Res 28:356-65
Dalton, Jo A; Higgins, Melinda K; Miller, Andrew H et al. (2015) Pain Intensity and Pain Interference in Patients With Lung Cancer: A Pilot Study of Biopsychosocial Predictors. Am J Clin Oncol 38:457-64
Reilly, Carolyn Miller; Higgins, Melinda; Smith, Andrew et al. (2015) Isolating the benefits of fluid restriction in patients with heart failure: A pilot study. Eur J Cardiovasc Nurs 14:495-505
Quinn, Christina; Dunbar, Sandra B; Clark, Patricia C et al. (2010) Challenges and strategies of dyad research: cardiovascular examples. Appl Nurs Res 23:e15-20
Su, Shaoyong; Zhao, Jinying; Bremner, J Douglas et al. (2009) Serotonin transporter gene, depressive symptoms, and interleukin-6. Circ Cardiovasc Genet 2:614-20
Su, Shaoyong; Lampert, Rachel; Zhao, Jinying et al. (2009) Pleiotropy of C-reactive protein gene polymorphisms with C-reactive protein levels and heart rate variability in healthy male twins. Am J Cardiol 104:1748-54
Quinn, Christina; Haber, Michael J; Pan, Yi (2009) Use of the concordance correlation coefficient when examining agreement in dyadic research. Nurs Res 58:368-73
Parker, Kathy P; Bliwise, Donald L; Ribeiro, Maria et al. (2008) Sleep/Wake patterns of individuals with advanced cancer measured by ambulatory polysomnography. J Clin Oncol 26:2464-72
Parker, Kathy P; Bailey, James L; Rye, David B et al. (2007) Lowering dialysate temperature improves sleep and alters nocturnal skin temperature in patients on chronic hemodialysis. J Sleep Res 16:42-50

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