Abstract

This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The objective of the Transgenic Core is to provide transgenic mice to members of the COBRE program. The availability of this Core will provide state of the art technologies to investigators skilled in pathology, molecular biology and lung disease. In addition to the generation, maintenance and screening of new transgenic mice, this Core aims to establish the techniques required for the generation of knock out mice at the University of Vermont.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR015557-08
Application #
7609699
Study Section
Special Emphasis Panel (ZRR1-RI-8 (02))
Project Start
2007-05-01
Project End
2008-04-30
Budget Start
2007-05-01
Budget End
2008-04-30
Support Year
8
Fiscal Year
2007
Total Cost
$247,316
Indirect Cost

  Institution

Name
University of Vermont & St Agric College
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405

  Publications

Szalayova, Gabriela; Ogrodnik, Aleksandra; Spencer, Brianna et al. (2016) Human breast cancer biopsies induce eosinophil recruitment and enhance adjacent cancer cell proliferation. Breast Cancer Res Treat 157:461-74
Cruz, Fernanda F; Borg, Zachary D; Goodwin, Meagan et al. (2016) CD11b+ and Sca-1+ Cells Exert the Main Beneficial Effects of Systemically Administered Bone Marrow-Derived Mononuclear Cells in a Murine Model of Mixed Th2/Th17 Allergic Airway Inflammation. Stem Cells Transl Med 5:488-99
Ather, Jennifer L; Burgess, Edward J; Hoyt, Laura R et al. (2016) Uricase Inhibits Nitrogen Dioxide-Promoted Allergic Sensitization to Inhaled Ovalbumin Independent of Uric Acid Catabolism. J Immunol 197:1720-32
Kasahara, David I; Ninin, Fernanda M C; Wurmbrand, Alison P et al. (2015) Abrogation of airway hyperresponsiveness but not inflammation by rho kinase insufficiency. Clin Exp Allergy 45:457-70
Lathrop, M J; Sage, E K; Macura, S L et al. (2015) Antitumor effects of TRAIL-expressing mesenchymal stromal cells in a mouse xenograft model of human mesothelioma. Cancer Gene Ther 22:44-54
Dixon, Anne E; Gerald, Lynn B (2015) Promoting weight loss in asthma. Respirology 20:179-80
Cruz, Fernanda F; Borg, Zachary D; Goodwin, Meagan et al. (2015) Freshly thawed and continuously cultured human bone marrow-derived mesenchymal stromal cells comparably ameliorate allergic airways inflammation in immunocompetent mice. Stem Cells Transl Med 4:615-24
Cruz, Fernanda F; Borg, Zachary D; Goodwin, Meagan et al. (2015) Systemic Administration of Human Bone Marrow-Derived Mesenchymal Stromal Cell Extracellular Vesicles Ameliorates Aspergillus Hyphal Extract-Induced Allergic Airway Inflammation in Immunocompetent Mice. Stem Cells Transl Med 4:1302-16
Menon, Prema R; Stapleton, Renee D; McVeigh, Ursula et al. (2015) Telemedicine as a tool to provide family conferences and palliative care consultations in critically ill patients at rural health care institutions: a pilot study. Am J Hosp Palliat Care 32:448-53
Lathrop, Melissa J; Brooks, Elice M; Bonenfant, Nick R et al. (2014) Mesenchymal stromal cells mediate Aspergillus hyphal extract-induced allergic airway inflammation by inhibition of the Th17 signaling pathway. Stem Cells Transl Med 3:194-205

Showing the most recent 10 out of 158 publications