This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Biological Specimens and Genetics (BSG) Core provides key services necessary to facilitate collaborative investigations between geneticists, statisticians, epidemiologists, psychologists, and community leaders that are aimed at understanding the interaction of obesity-related risk factors in Yup'ik Eskimos. Additionally, the BSG core provides valuable community, and state-wide services related to the ethical conduct of culturally respectful genetic studies in rural Alaska Native communities. The BSG Core accomplishes these objectives by advising new investigators on the role of heredity in disease etiology, and on the ascertainment of familial relationships using methods that maximize the privacy of participating and non-participating community members. The BSG Core ensures that biological samples are processed to retain sample integrity and stored in a secure facility, and maintains a specimen database to manage and track samples shipped to collaborating laboratories. In addition, the BSG Core provides genotyping expertise to new investigators and students. The design of the BSG Core is based on our experiences and use of the Genetics Core in phase I of the CANHR study, and on the stated health priorities of our community partners and Tribal Elders.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016430-10
Application #
8360228
Study Section
Special Emphasis Panel (ZRR1-RI-5 (01))
Project Start
2011-07-01
Project End
2012-09-14
Budget Start
2011-07-01
Budget End
2013-06-30
Support Year
10
Fiscal Year
2011
Total Cost
$61,671
Indirect Cost
Name
University of Alaska Fairbanks
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
615245164
City
Fairbanks
State
AK
Country
United States
Zip Code
99775
Philip, Jacques; Ryman, Tove K; Hopkins, Scarlett E et al. (2017) Bi-cultural dynamics for risk and protective factors for cardiometabolic health in an Alaska Native (Yup'ik) population. PLoS One 12:e0183451
Power, Julianne M; Braun, Kathryn L; Bersamin, Andrea (2017) Exploring the Potential for Technology-Based Nutrition Education Among WIC Recipients in Remote Alaska Native Communities. J Nutr Educ Behav 49:S186-S191.e1
Fohner, Alison E; Wang, Zhican; Yracheta, Joseph et al. (2016) Genetics, Diet, and Season Are Associated with Serum 25-Hydroxycholecalciferol Concentration in a Yup'ik Study Population from Southwestern Alaska. J Nutr 146:318-25
Lardon, Cécile; Wolsko, Christopher; Trickett, Edison et al. (2016) Assessing health in an Alaska native cultural context: The Yup'ik Wellness Survey. Cultur Divers Ethnic Minor Psychol 22:126-36
Philip, Jacques; Ford, Tara; Henry, David et al. (2016) Relationship of Social Network to Protective Factors in Suicide and Alcohol Use Disorder Intervention for Rural Yup'ik Alaska Native Youth. Interv Psicosoc 25:45-54
Aslibekyan, Stella; Vaughan, Laura K; Wiener, Howard W et al. (2016) Linkage and association analysis of circulating vitamin D and parathyroid hormone identifies novel loci in Alaska Native Yup'ik people. Genes Nutr 11:23
Lemas, Dominick J; Klimentidis, Yann C; Aslibekyan, Stella et al. (2016) Polymorphisms in stearoyl coa desaturase and sterol regulatory element binding protein interact with N-3 polyunsaturated fatty acid intake to modify associations with anthropometric variables and metabolic phenotypes in Yup'ik people. Mol Nutr Food Res 60:2642-2653
Moses, Sara K; Harley, John R; Lieske, Camilla L et al. (2015) Variation in bioaccumulation of persistent organic pollutants based on octanol-air partitioning: Influence of respiratory elimination in marine species. Mar Pollut Bull 100:122-7
Hopkins, S E; Austin, M A; Metzger, J S et al. (2015) Sex differences in obesity prevalence and cardiometabolic factors among Western Alaska Native people. Nutr Metab Cardiovasc Dis 25:312-8
Beaulieu-Jones, Brendin R; O'Brien, Diane M; Hopkins, Scarlett E et al. (2015) Sex, Adiposity, and Hypertension Status Modify the Inverse Effect of Marine Food Intake on Blood Pressure in Alaska Native (Yup'ik) People. J Nutr 145:931-8

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