The Mississippi IDeA Networks of Biomedical Research Excellence (MS-INBRE) project has significantly enhanced biomedical research and training in the State via the establishment of eight research laboratories at our partner undergraduate institutions (PUl), access to core research and bioinformatics facilities, grantsmanship training and over 200 hands-on student research internships. We will continue to strengthen the research capacity of the State and train the future generation of scientists via expanding our Network to six PUI: Alcorn State University, Millsaps College, Mississippi College, Mississippi University for Women, Mississippi Valley State University and Tougaloo College. We will support and mentor nine promising faculty researchers at these partner institutions engaged in basic research in one of the focus areas of particular concern to Mississippi: Cardiovascular Disease, Cancer or Infectious Disease. These diseases are major causes of death and disability in Mississippi and of particular concern for health disparities populations in the State. Dedicated mentors will interact closely with each PUI researcher to facilitate the development of their independent research. In a major new initiative, the Bioinformatics Core will be expanded to include faculty from all doctoral institutions. We will enhance the capabilities of the Genomics Core Facility and Imaging Core Facility for the use of PUI and other researchers in Mississippi. Two additional Core facilities, Proteomics Core and Analytical Core, will be added. In addition, we will provide professional development workshops on grantsmanship, bioinformatics, scientific publications/presentations, etc. as well as organize a Distinguished Scientist Seminar Series to be held at our Partner Institutions. The Outreach Core will focus on expanding the highly successful undergraduate Research Experience Opportunity summer internship program and assisting the 8 Outreach Institutions in the Network. Outreach efforts include Grants-in-Aid and Outreach Mini-Grants which will provide small equipment seed grants and travel funds for professional development workshops/conferences, etc. The MS-INBRE scientific network, mentoring, training and outreach will enhance biomedical research today and reach into the next generations as we train students who will be the researchers and policy makers of the future.

Public Health Relevance

The major causes of death are cardiovascular disease and cancer, followed by infectious diseases. It is vital that we tap all available brainpower to combat these diseases by mentoring and training researchers now as well as the scientists of the future - the students of today.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
5P20RR016476-10
Application #
8129624
Study Section
Special Emphasis Panel (ZRR1-RI-7 (01))
Program Officer
Gorospe, Rafael
Project Start
2001-09-20
Project End
2013-05-31
Budget Start
2011-06-01
Budget End
2012-05-31
Support Year
10
Fiscal Year
2011
Total Cost
$3,007,108
Indirect Cost
Name
University of Southern Mississippi
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
623335775
City
Hattiesburg
State
MS
Country
United States
Zip Code
39406
Das, Pradipta K; Dean, Dexter N; Fogel, April L et al. (2017) Aqueous RAFT Synthesis of Glycopolymers for Determination of Saccharide Structure and Concentration Effects on Amyloid ? Aggregation. Biomacromolecules 18:3359-3366
Rana, Pratip; Dean, Dexter N; Steen, Edward D et al. (2017) Fatty Acid Concentration and Phase Transitions Modulate A? Aggregation Pathways. Sci Rep 7:10370
Budachetri, Khemraj; Crispell, Gary; Karim, Shahid (2017) Amblyomma maculatum SECIS binding protein 2 and putative selenoprotein P are indispensable for pathogen replication and tick fecundity. Insect Biochem Mol Biol 88:37-47
Budachetri, Khemraj; Williams, Jaclyn; Mukherjee, Nabanita et al. (2017) The microbiome of neotropical ticks parasitizing on passerine migratory birds. Ticks Tick Borne Dis 8:170-173
Dean, Dexter N; Das, Pradipta K; Rana, Pratip et al. (2017) Strain-specific Fibril Propagation by an A? Dodecamer. Sci Rep 7:40787
Budachetri, K; Kumar, D; Karim, S (2017) Catalase is a determinant of the colonization and transovarial transmission of Rickettsia parkeri in the Gulf Coast tick Amblyomma maculatum. Insect Mol Biol 26:414-419
Ghosh, Preetam; Vaidya, Ashwin; Kumar, Amit et al. (2016) Determination of critical nucleation number for a single nucleation amyloid-? aggregation model. Math Biosci 273:70-9
Amato, Dahlia N; Amato, Douglas V; Mavrodi, Olga V et al. (2016) Destruction of Opportunistic Pathogens via Polymer Nanoparticle-Mediated Release of Plant-Based Antimicrobial Payloads. Adv Healthc Mater 5:1094-103
Chakraborty, Sandipan; Kumar, Avinash; Butt, Nasir A et al. (2016) Molecular insight into the differential anti-androgenic activity of resveratrol and its natural analogs: in silico approach to understand biological actions. Mol Biosyst 12:1702-9
Chakraborty, S; Asare, B K; Biswas, P K et al. (2016) Designer interface peptide grafts target estrogen receptor alpha dimerization. Biochem Biophys Res Commun 478:116-122

Showing the most recent 10 out of 139 publications