The Administrative Core is charged with leadership, oversight, fiscal, and general administrative responsibility for the Oregon Alzheimer Disease Center (OADC). The OADC Director works closely with the Executive Committee of the Center, which is composed of all the Core Leaders and other key OADC personnel. The Administrative Core coordinates the six cores of the Center through structured, regular meetings and interim reports. Members of individual Cores, having duties and necessary interactions within other related units of the Center, facilitate the integration of the OADC on a daily basis. In addition to managerial and supervisory duties, the Administrative Core also seeks to ensure that the OADC is positioned to respond to the needs of the greater community of scientists and other interested individuals engaged in activities relevant to research on Alzheimer disease and related disorders, especially as they relate to uncompromised brain aging and incipient or early dementia. This includes advising and encouraging young investigators, as well as relating to the concerns and requirements of established scientists with regard to their research. The Core also seeks to foster the movement of talented investigators from other fields into the brain aging and dementia arena. This process is facilitated by the OADC Pilot Project Grant mechanism organized annually by the Administrative Core. Overview of the general direction and quality of the Center is achieved through oversight and advice of the National Institute on Aging and two committees: the External and Internal Advisory Committees. The External Review process brings in an outside External Review Committee of experts to critically review the progress of the Center and issue a formal report. Similarly, but with a different, yet complementary perspective, the Internal Advisory Committee (composed of prominent local scientists and community leaders) also provides review and oversight to the OADC. Members of both review committees are also used to advise the OADC Director and Core Leaders on an as needed basis as well.

Public Health Relevance

The Administrative Core of the Oregon Alzheimer Disease Center provides the necessary organizational structure, scientific direction and leadership to effectively operate the entire research center. In providing oversight and stewardship of the overall mission of the center sound fiscal, scientific and educational policies and practices are achieved targeted toward the goal of understanding the causes of dementia and ultimately their treatments.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Oregon Health and Science University
United States
Zip Code
Deming, Yuetiva; Dumitrescu, Logan; Barnes, Lisa L et al. (2018) Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol 136:857-872
Besser, Lilah; Kukull, Walter; Knopman, David S et al. (2018) Version 3 of the National Alzheimer's Coordinating Center's Uniform Data Set. Alzheimer Dis Assoc Disord 32:351-358
Tse, Kai-Hei; Cheng, Aifang; Ma, Fulin et al. (2018) DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer's disease and dementia. Alzheimers Dement 14:664-679
Crum, Jana; Wilson, Jeffrey; Sabbagh, Marwan (2018) Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer's dementia? Alzheimers Res Ther 10:104
Schaffert, Jeff; LoBue, Christian; White, Charles L et al. (2018) Traumatic brain injury history is associated with an earlier age of dementia onset in autopsy-confirmed Alzheimer's disease. Neuropsychology 32:410-416
Burke, Shanna L; Cadet, Tamara; Maddux, Marlaina (2018) Chronic Health Illnesses as Predictors of Mild Cognitive Impairment Among African American Older Adults. J Natl Med Assoc 110:314-325
Blue, Elizabeth E; Bis, Joshua C; Dorschner, Michael O et al. (2018) Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dement Geriatr Cogn Disord 45:1-17
Kamara, Dennis M; Gangishetti, Umesh; Gearing, Marla et al. (2018) Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease. J Alzheimers Dis 62:1815-1826
Lusardi, Theresa A; Wiedrick, Jack T; Malone, Molly et al. (2018) Analytics of Cerebrospinal Fluid MicroRNA Quantitative PCR Studies. Mol Neurobiol :
Leach, Julia M; Mancini, Martina; Kaye, Jeffrey A et al. (2018) Day-to-Day Variability of Postural Sway and Its Association With Cognitive Function in Older Adults: A Pilot Study. Front Aging Neurosci 10:126

Showing the most recent 10 out of 482 publications