The Administrative Core provides overall scientific and administrative supervision and coordination of the ADC. The ADC Director is the Administrative Core Leader. He is assisted by eight Core Leaders and/or Senior Investigators who serve as Associate Administrative Core Leaders, and who together with the Director and ADC Administrator form the Center's Executive Committee. Day-to-day administration and fiscal management is carried out by the Center Administrator and Administrative Assistant. The Executive Committee, with the assistance of the Administrator, implements the policies and pursues goals of the ADC. The Executive Committee interacts directly with the Core Leaders and with the heads of the affiliated research programs and projects. The Director and Executive Committee receive guidance and assistance External Advisory Committee, which meets annually to review progress and scientific productivity and to make recommendations for strengthening the Center. Pilot Study proposals are reviewed each year by a Pilot Study Review Committee and are approved by the Executive Committee. During the past 5-years, the Administrative Core has continued to improve the well-established administrative structure and procedures necessary to achieve its goals. The procedures and administrative functions of the core have evolved with the continuing growth and success of the ADC. Regular ADC meetings provide a forum for establishing and implementing ADC policies, monitoring progress of the Cores, reviewing and disseminating recent research, and stimulating new research and research collaborations. There has been substantial growth in the productivity of the ADC, as evidenced by increases in the number of grants and projects using ADC resources, the extent of utilization of subjects, data and biological samples, and the number of publications associated with the ADC. There has also been increased collaboration with national consortia and outside investigators. Successful initiatives during the current grant period have included strengthening the productivity of the pilot study program, contributing to the establishment of the new Center of Excellence (CoE) on Brain Aging, and with the CoE, enhancing core resources to include Biorepository and Clinical Trials Cores. These developments serve to strengthen the ADC's scientific focus on early diagnosis and prevention of AD.

Public Health Relevance

The Administrative Core is essential for the sucessful operation and coordination of the ADC. Thus the Administrafice Core enables the ADC to achieve its scientific and public health goal- the early diagnosis and prevention of Alzheimer's disease.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG008051-25
Application #
8672569
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4)
Project Start
Project End
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
25
Fiscal Year
2014
Total Cost
$304,835
Indirect Cost
$124,155
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
John, Samantha E; Gurnani, Ashita S; Bussell, Cara et al. (2016) The effectiveness and unique contribution of neuropsychological tests and the δ latent phenotype in the differential diagnosis of dementia in the uniform data set. Neuropsychology 30:946-960
Bonham, Luke W; Geier, Ethan G; Fan, Chun C et al. (2016) Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease. Ann Clin Transl Neurol 3:668-77
Brown, Ryan; Lakshmanan, Karthik; Madelin, Guillaume et al. (2016) A nested phosphorus and proton coil array for brain magnetic resonance imaging and spectroscopy. Neuroimage 124:602-11
Ting, Simon Kang Seng; Hao, Ying; Chia, Pei Shi et al. (2016) Clinicopathological correlation of psychosis and brain vascular changes in Alzheimer's disease. Sci Rep 6:20858
Fischer, Corinne E; Qian, Winnie; Schweizer, Tom A et al. (2016) Lewy Bodies, Vascular Risk Factors, and Subcortical Arteriosclerotic Leukoencephalopathy, but not Alzheimer Pathology, are Associated with Development of Psychosis in Alzheimer's Disease. J Alzheimers Dis 50:283-95
Karch, Celeste M; Ezerskiy, Lubov A; Bertelsen, Sarah et al. (2016) Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. PLoS One 11:e0148717
Tosto, Giuseppe; Monsell, Sarah E; Hawes, Stephen E et al. (2016) Progression of Extrapyramidal Signs in Alzheimer's Disease: Clinical and Neuropathological Correlates. J Alzheimers Dis 49:1085-93
McCutcheon, Sarah T; Han, Dingfen; Troncoso, Juan et al. (2016) Clinicopathological correlates of depression in early Alzheimer's disease in the NACC. Int J Geriatr Psychiatry 31:1301-1311
Chapman, Kimberly R; Bing-Canar, Hanaan; Alosco, Michael L et al. (2016) Mini Mental State Examination and Logical Memory scores for entry into Alzheimer's disease trials. Alzheimers Res Ther 8:9
Wisniewski, Thomas; Drummond, Eleanor (2016) Developing therapeutic vaccines against Alzheimer's disease. Expert Rev Vaccines 15:401-15

Showing the most recent 10 out of 444 publications