The Psychosocial Core has grown in scope and broadened its research agenda since its inception in 1998. The evolution of the program of the Psychosocial Core is concordant with the themes of the NYU-ADC. focusing on older adults with subjective complaints of cognitive impairment and the earliest stages of memory loss as well as its original focus on family caregivers of older adults across the entire course of AD. Our affiliated Psychosocial Research Program has conducted or is currently supporting several projects to understand and ameliorate the emotional consequences of the symptoms of mild cognitive impairment (MCI) and Alzheimer's disease (AD). The Psychosocial Core conducts a comprehensive assessment of the primary caregivers of all subjects participating in the Clinical Core, and family members of those with MCI and AD. follows them longitudinally and provides them with counseling on request. The routine structured multifaceted assessment is in two parts: the first part includes measures of depression, anxiety, social network and support and quality of life;the second part measures family conflict, behavior problems and caregiver reaction, caregiver appraisal, formal and informal support utilization and other specific characteristics related to caregiving. Family members of patients with AD complete the entire assessment. Subjects with MCI, their study partners and cognitively normal subjects who are not caregivers complete only the first part of this assessment. At the conclusion of every diagnostic evaluation of the Clinical Core, counselors of the Psychosocial Core conduct conferences with the subject, primary caregiver (if appropriate) and other family members. The counseling staff is available to respond to requests for help and information, are a user-friendly resource and a link between center subjects and other center staff. Their activities facilitate recruitment of new subjects, retention of current subjects and participation of subjects in autopsy tracking and in research studies. The Psychosocial Core data is a resource for the research of the NYU Psychosocial Research Program, and for other collaborating investigators in the field. The large database and subject pool, to which we will continue to add new subjects and longitudinal information, will be a valuable research resource in its own right and foster the formulation of new research to improve caregiver and patient well-being.

Public Health Relevance

The Psychosocial Core provides counseling and support for all participants of the ADC and their family members. By conducting a comprehensive psychological and emotional assessment, the Psychosocial Core has developed a rich database for research into the effects of cognitive dysfunction at all levels on the individual and on the family and is a source of participants for studies of interventions in the ADC-affiliated Psychosocial Research Program.

Agency
National Institute of Health (NIH)
Type
Center Core Grants (P30)
Project #
5P30AG008051-25
Application #
8672576
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
Budget End
Support Year
25
Fiscal Year
2014
Total Cost
Indirect Cost
Name
New York University
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Galvin, James E; Tolea, Magdalena I; George, Nika et al. (2014) Public-private partnerships improve health outcomes in individuals with early stage Alzheimer's disease. Clin Interv Aging 9:621-30
Grill, Joshua D; Galvin, James E (2014) Facilitating Alzheimer disease research recruitment. Alzheimer Dis Assoc Disord 28:1-8
Salloway, Stephen; Sperling, Reisa; Fox, Nick C et al. (2014) Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. N Engl J Med 370:322-33
Mosconi, Lisa; Murray, John; Tsui, Wai H et al. (2014) Brain imaging of cognitively normal individuals with 2 parents affected by late-onset AD. Neurology 82:752-60
Sabharwal, Priyanka; Wisniewski, Thomas (2014) Novel immunological approaches for the treatment of Alzheimer's disease. Zhongguo Xian Dai Shen Jing Ji Bing Za Zhi 14:139-151
Zhang, Ying; Shi, Zhihong; Liu, Mengyuan et al. (2014) Prevalence of cognitive impairment no dementia in a rural area of Northern China. Neuroepidemiology 42:197-203
Butler, Tracy; Zaborszky, Laszlo; Pirraglia, Elizabeth et al. (2014) Comparison of human septal nuclei MRI measurements using automated segmentation and a new manual protocol based on histology. Neuroimage 97:245-51
Reisberg, Barry; Monteiro, Isabel; Torossian, Carol et al. (2014) The BEHAVE-AD assessment system: a perspective, a commentary on new findings, and a historical review. Dement Geriatr Cogn Disord 38:89-146
Iulita, M Florencia; Do Carmo, Sonia; Ower, Alison K et al. (2014) Nerve growth factor metabolic dysfunction in Down's syndrome brains. Brain 137:860-72
Jessen, Frank; Amariglio, Rebecca E; van Boxtel, Martin et al. (2014) A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimers Dement 10:844-52

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