The Indiana Alzheimer Disease Center (lADC) is established on the campus of Indiana University School of Medicine. It is comprised of six cores: Administrative Core, Clinical Core, Data Management and Statistics Core, Neuropathology Core, Education and Information Transfer Core and Neuroimaging Core. The mission of the lADC is: 1) to support and carry out research on Alzheimer disease (AD) and other neurodegenerative dementias, 2) to serve as shared research resources that will facilitate research in AD and other dementias, 3)distinguish them from the processes of normal brain aging and mild cognitive impairment (MCI), 4) provide a platform for training, 5) develop novel techniques and methodologies, and 6) translate these research findings into better diagnostic, prevention and treatment strategies. The focus of the lADC is on behavioral neurology, clinico- pathological correlations, biochemistry, and genetics of AD, front temporal dementia and Parkinsonism linked to chromosome 17 (FTDP-17), Gerstmann-Straussler-Schelnker disease (GSS), Parkinson disease and other hereditary diseases associated with abnormal protein accumulation.
It is estimated that as many as 5 million Americans have AD. The Indiana Alzheimer Disease Center provides an environment and resources directed towards fostering and coordinating research and educational activities on AD and other dementing illnesses.
|Li, Huang; Fang, Shiaofen; Contreras, Joey A et al. (2017) Brain explorer for connectomic analysis. Brain Inform 4:253-269|
|Yao, Xiaohui; Yan, Jingwen; Ginda, Michael et al. (2017) Mapping longitudinal scientific progress, collaboration and impact of the Alzheimer's disease neuroimaging initiative. PLoS One 12:e0186095|
|Sano, Mary; Zhu, Carolyn W; Grossman, Hillel et al. (2017) Longitudinal Cognitive Profiles in Diabetes: Results From the National Alzheimer's Coordinating Center's Uniform Data. J Am Geriatr Soc 65:2198-2204|
|Sokolow, Sophie; Li, Xiaohui; Chen, Lucia et al. (2017) Deleterious Effect of Butyrylcholinesterase K-Variant in Donepezil Treatment of Mild Cognitive Impairment. J Alzheimers Dis 56:229-237|
|Tripodis, Yorghos; Alosco, Michael L; Zirogiannis, Nikolaos et al. (2017) The Effect of Traumatic Brain Injury History with Loss of Consciousness on Rate of Cognitive Decline Among Older Adults with Normal Cognition and Alzheimer's Disease Dementia. J Alzheimers Dis 59:251-263|
|Jefferson-George, Kyra S; Wolk, David A; Lee, Edward B et al. (2017) Cognitive decline associated with pathological burden in primary age-related tauopathy. Alzheimers Dement 13:1048-1053|
|Brenowitz, Willa D; Hubbard, Rebecca A; Keene, C Dirk et al. (2017) Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample. Alzheimers Dement 13:654-662|
|Brosch, Jared R; Farlow, Martin R; Risacher, Shannon L et al. (2017) Tau Imaging in Alzheimer's Disease Diagnosis and Clinical Trials. Neurotherapeutics 14:62-68|
|Jutkowitz, Eric; Kane, Robert L; Gaugler, Joseph E et al. (2017) Societal and Family Lifetime Cost of Dementia: Implications for Policy. J Am Geriatr Soc 65:2169-2175|
|Garringer, Holly J; Sammeta, Neeraja; Oblak, Adrian et al. (2017) Amyloid and intracellular accumulation of BRI2. Neurobiol Aging 52:90-97|
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