Abstract

The purpose of the Administrative Core is (1) to provide overall direction and provide fiscal management for the Indiana Alzheimer Disease Center (IADC), (2) to coordinate and integrate the activities of the IADC components, (3) to encourage research into Alzheimer disease (AD) and related disorders by the faculty at Indiana University School of Medicine and (4) to encourage, evaluate, support and supervise the conduct of the pilot project. The Core Leader is Dr. Bernardino Ghetti. He will be assisted by an Associate Co-Director Dr. Martin R. Farlow. One of the IADC missions is that of nurturing new research in AD and related dementias and of encouraging new investigators to develop research interests in areas of AD. Two pilot projects will be available annually through the IADC. Junior investigators from Indiana University are encouraged to apply. A call for research proposals will be made annually to all chairpersons and directors of centers, institutes and divisions within Indiana University and Purdue University as well as other selected institutions that do not have an Alzheimer disease center.

Public Health Relevance

It is estimated that as many as 5 million Americans have AD. The Indiana Alzheimer Disease Center provides an environment and resources directed towards fostering and coordinating research and educational activities on AD and other dementing illnesses.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG010133-23
Application #
8502588
Study Section
Special Emphasis Panel (ZAG1-ZIJ-5)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
23
Fiscal Year
2013
Total Cost
$259,972
Indirect Cost
$91,160

  Institution

Name
Indiana University-Purdue University at Indianapolis
Department
Type
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202

  Publications

Haaksma, Miriam L; Calderón-Larrañaga, Amaia; Olde Rikkert, Marcel G M et al. (2018) Cognitive and functional progression in Alzheimer disease: A prediction model of latent classes. Int J Geriatr Psychiatry 33:1057-1064
Campbell, Noll L; Lane, Kathleen A; Gao, Sujuan et al. (2018) Anticholinergics Influence Transition from Normal Cognition to Mild Cognitive Impairment in Older Adults in Primary Care. Pharmacotherapy 38:511-519
Ganguli, Mary; Albanese, Emiliano; Seshadri, Sudha et al. (2018) Population Neuroscience: Dementia Epidemiology Serving Precision Medicine and Population Health. Alzheimer Dis Assoc Disord 32:1-9
Yan, Jingwen; Liu, Kefei; Li, Huang et al. (2018) JOINT EXPLORATION AND MINING OF MEMORY-RELEVANT BRAIN ANATOMIC AND CONNECTOMIC PATTERNS VIA A THREE-WAY ASSOCIATION MODEL. Proc IEEE Int Symp Biomed Imaging 2018:6-9
Ramsey, Christine M; Gnjidic, Danijela; Agogo, George O et al. (2018) Longitudinal patterns of potentially inappropriate medication use following incident dementia diagnosis. Alzheimers Dement (N Y) 4:1-10
Murray, Michael D; Hendrie, Hugh C; Lane, Kathleen A et al. (2018) Antihypertensive Medication and Dementia Risk in Older Adult African Americans with Hypertension: A Prospective Cohort Study. J Gen Intern Med 33:455-462
Wang, Sophia; Allen, Duane; Kheir, You Na et al. (2018) Aging and Post-Intensive Care Syndrome: A Critical Need for Geriatric Psychiatry. Am J Geriatr Psychiatry 26:212-221
Apostolova, Liana G; Risacher, Shannon L; Duran, Tugce et al. (2018) Associations of the Top 20 Alzheimer Disease Risk Variants With Brain Amyloidosis. JAMA Neurol 75:328-341
Wang, Xiaoqian; Chen, Hong; Yan, Jingwen et al. (2018) Quantitative trait loci identification for brain endophenotypes via new additive model with random networks. Bioinformatics 34:i866-i874
Li, Wei; Risacher, Shannon L; Gao, Sujuan et al. (2018) Type 2 diabetes mellitus and cerebrospinal fluid Alzheimer's disease biomarker amyloid ?1-42 in Alzheimer's Disease Neuroimaging Initiative participants. Alzheimers Dement (Amst) 10:94-98

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